The information provided is not a substitute for any medical advice. Therefore, you should always consult with your doctor or pharmacist before using any medication.
What is the dose for an adult?
Individualize the starting dose of Janumet based on the patient’s current regimen. May adjust the dosing based on effectiveness and tolerability while not exceeding the maximum recommended daily dose of 100 mg sitagliptin and 2000 mg metformin.
The recommended starting dose in patients not currently treated with metformin:
50 mg sitagliptin/500 mg metformin hydrochloride twice daily, with gradual dose escalation recommended to reduce gastrointestinal side effects associated with metformin.
The starting dose in patients already treated with metformin:
Sitagliptin dosed as 50 mg twice daily (100 mg total daily dose) and the dose of metformin already being taken.
For patients taking metformin 850 mg twice daily, the recommended starting dose of Janumet is 50 mg sitagliptin/1000 mg metformin hydrochloride twice daily.
What is the dose for a child?
The dosage has not been established in pediatric patients (younger than 18 years old). It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.
How is Janumet available?
Janumet is available in the following dosage forms and strengths:
- Film-coated tablets 50mg sitagliptin/500mg metformin (Janumet)
- Film-coated tablets 50mg sitagliptin/1000mg metformin (Janumet XR)
What should I do in case of an emergency or overdose?
In case of an emergency or an overdose, call your local emergency services or go to the nearest emergency room.
What should I do if I miss a dose?
If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.
Janumet. http://www.Janumetxr.com/sitagliptin_metformin_HCL/Janumetxr/consumer/what-is-Janumet/index.xhtml. Accessed October 07, 2016.
Janumet. http://www.merck.com/product/usa/pi_circulars/j/Janumet/Janumet_pi.pdf. Accessed October 07, 2016.
Janumet. https://www.medicines.org.uk/emc/medicine/23111. Accessed October 07, 2016.
Janumet® (Sitagliptin, Metformin). http://www.fda.gov/downloads/drugs/drugsafety/ucm204268.pdf. Accessed October 07, 2016.