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Menthol (peppermint oil)

Written by Stephanie Nera, RPh, PharmD · Pharmacology


Updated Jan 25, 2021

Uses

Uses of menthol

Menthol is an ingredient found in many topical and oral preparations as both a flavoring, counterirritant, mild local anesthetic. It is used for minor pain and cold symptoms. Menthol is a compound derived from mint plants, typically peppermint oil. Other sources of menthol include spearmint and corn mint.

How should I take menthol?

Because menthol is available in combination products, it should be applied as directed on the packaging.

For topical preparations (e.g. oils, creams, ointments):

benefits of moisturizing your skin

First, apply a thin layer of product to the affected area. Gently rub the skin to allow the product to be absorbed. Afterward, thoroughly wash your hand with soap and water.

In addition, avoid touching your eyes, mucous membranes, or any open wounds. In case some product gets into these areas, quickly rinse it with clean, running water.

For oral preparations (e.g. mouthwashes, oil, lozenges):

For mouthwashes and toothpastes, use about 20 mL of the solution or a pea-sized amount. Gently swish and gargle the mouthwash solution for 30 to 60 seconds. For toothpaste, gently brush your teeth using a toothbrush for 2 minutes. Do not swallow.

For lozenges, place one piece onto your tongue or cheek and allow it to dissolve slowly. Do not bite or chew the lozenge. In addition, avoid giving children lozenges as they mistake it for candy and it can be a choking hazard.

For oils, it may be necessary to mix the menthol in another liquid. Mix and drink the solution as directed.

Proper storage conditions

Store at room temperature, away from moisture and direct sunlight. To prevent drug damage, you should not store it in the bathroom or the freezer. There may be different brands of this drug that may have different storage needs. Therefore, it is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush it down the toilet or pour them into a drain unless instructed to do so. Additionally, do not use it if expired. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using menthol?

Before using this drug, tell your doctor if you:

  • Are pregnant or breastfeeding
  • Are taking other medications
  • Have ever had an allergic reaction to any medication
  • Have any allergies to any ingredient in the preparation
  • Currently have any cuts or wounds

Side effects

What are the side effects of menthol?

As with other medications, this drug may have side effects. However, most of side effects are uncommon and typically resolve after you stop taking the drug.

Potential side effects while using this drug include:

  • Irritation (nose, eyes, skin)
  • Skin redness
  • Burning sensation
  • Gastrointestinal disturbances (when taken orally)
  • Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side effect, please consult your doctor or pharmacist.

    Interactions

    What drugs may interact with menthol?

    This drug may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects.

    To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist.

    For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

    Does food or alcohol interact with menthol?

    Menthol may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist regarding any potential food or alcohol interactions before using this drug.

    What health conditions may interact with menthol?

    Menthol may not be suitable for people with sensitive skin or wounds. This may worsen your health condition or alter the way the drug works. Therefore, it is important to always let your doctor and pharmacist know all the health conditions you currently have.

    Dosage

    The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this drug.

    What is the dose for an adult?

    For cough

    • Menthol topical – oral lozenge:
      • Sore Throat: Dissolve 1 drop slowly in mouth every 2 hours as needed.
      • Cough: Dissolve 1 drop slowly in mouth every hour as needed.

    For pain

    • 2% gel, 2.5% gel, menthol topical 5% pad, 1.4% pad, and 1.25% pad.
    • 7% topical gel: Apply topically to affected area 3 to 4 times daily.
    • 6% spray and 10% spray: Spray topically to affected area as needed not to exceed 4 times a day.

    For pruritus (itchy skin)

    • 0.15% or 0.5% topical lotion: Apply topically to affected area 3 to 4 times daily.

    What is the dose for a child?

    For cough

    • Menthol topical – oral lozenge: 4 years or older:
    • Sore Throat: Dissolve 1 drop slowly in mouth every 2 hours as needed.
    • Cough: Dissolve 1 drop slowly in mouth every hour as needed.

    For pain

    • Menthol topical 1.4% pad, 1.25% pad, and menthol 7% topical gel:
      • 12 years or older: Apply topically to affected area 3 to 4 times daily.
    • Menthol topical 5% pad:
      • 10 years or older: Apply topically to affected area 3 to 4 times daily.
    • Menthol topical 6% spray:
      • 13 years or older: Spray topically to affected area as needed not to exceed 4 times a day.
    • Menthol topical 2% topical gel:
      • 2 years or older: Apply topically to affected area 3 to 4 times daily.
    • Menthol topical 2.5% topical gel:
  • 12 years or older: Apply topically to affected area no more than 4 times daily.
  • For pruritus (itchy skin)

    • 2 years and older:
      • Menthol 0.15% or 0.5% topical lotion: Apply topically to affected area 3 to 4 times daily.

    How is menthol available?

    Menthol is available in the following dosage forms and strengths:

    • Ointment, Topical: 27 mg/g.
    • Lozenge, oral: 3 mg

    What should I do in case of an emergency or overdose?

    In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

    What should I do if I miss a dose?

    If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

    Disclaimer

    Hello Health Group does not provide medical advice, diagnosis or treatment.

    Written by

    Stephanie Nera, RPh, PharmD

    Pharmacology


    Updated Jan 25, 2021

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