This drug may be excreted in breast milk. It drug should be used while breastfeeding only if the potential benefit justifies the potential risk to the child, as determined by your doctor.
Side effects
What side effects can occur when using tobramycin?
Like all drugs, this product may have side effects. If they occur, side effects are generally mild and resolve once treatment is finished or the dose is lowered. Some reported side effects include:
- Localized ocular toxicity
- Conjunctival erythema (redness)
- Punctate keratitis
- Increased lacrimation (tear production)
Rare, serious adverse reactions:
- Neurotoxicity
- Nephrotoxicity
- Anaphylactic reaction
- Exfoliative dermatitis
- Toxic epidermal necrolysis (TEN)
- Stevens-Johnson syndrome (SJS)
- Erythema multiforme
- Neuromuscular blockage or respiratory paralysis
However, not everyone experiences these side effects. In addition, some people may experience other side effects. So, if you have any concerns about a side effect, please consult your doctor or pharmacist.
Interactions
What drugs may interact with tobramycin?
This medication may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects.
To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist.
Drugs with known interactions:
- Allopurinol
- Amphotericin B cholesteryl sulfate complex
- Azithromycin
- Heparin
- Hetastarch in NS
- Indomethacin
- Pantoprazole
- Pemetrexed
- Piperacillin (with or without tazobactam)
- Propofol
- Sargramostim
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