What drugs may interact with cefazolin?
This medication may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects.
To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist.
Drugs with known interactions:
- Enhanced anticoagulant effect
- Sodium picosulfate
- Decreased therapeutic effect of this drug
- BCG and typhoid vaccine
- Decreased therapeutic effect of these vaccines
- Fosphenytoin and phenytoin
- Decreased protein binding of these drugs
- Decreased clearance of cefazolin
This drug is incompatible with the following:
- Amphotericin B cholesteryl sulfate complex
- Hetastarch in NS
If you experience an adverse drug interaction, stop taking this drug and continue taking your other medication. Inform your doctor immediately to reevaluate your treatment plan. Approaches include dose adjustment, drug substitution, or ending therapy.
Does food or alcohol interact with cefazolin?
This drug can be taken with or without meals, as there is no notable interaction. Do not take this medication with alcohol as it may induce a disulfiram-like reaction, including symptoms such as nausea, vomiting, flushing, dizziness, chest and abdominal discomfort, and hangover-like symptoms.
Inform your doctor or pharmacist if you have any concerns regarding food-drug interactions.
What health conditions may interact with cefazolin?
This drug should be taken with caution if you have any of the following conditions or risk factors:
- History of hypersensitivity to penicillins
- Renal impairment
- GI disease
- Clostridium difficile-associated diarrhea
- Seizure disorder
Inform your doctor or pharmacist if you have any concerns regarding specific health conditions.