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Robitussin (Guaifenesin, Expectorant)

Written by Stephanie Nera, RPh, PharmD · Pharmacology

Updated Jul 25, 2022

Robitussin (Guaifenesin, Expectorant)

Robitussin is the brand name of the drug guaifenesin. Guaifenesin is an expectorant that helps you clear phlegm from your chest and throat.



What is Robitussin used for?

How should I take Robitussin?

Read the directions on the packaging for complete information. Check the label and expiration date.

For oral dosage forms, swallow it whole without chewing, crushing, or dissolving it in liquid.

When measuring your doses, use a medical-grade measuring cup not a household spoon.

How do I store Robitussin?

Store this product at room temperature away from direct light and moisture. To prevent drug damage, you should not store it in the bathroom or the freezer. 

There may be different brands of this drug that may have different storage needs. So, it is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush this product down the toilet or pour them into a drain unless instructed to do so. Additionally, it is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & Warnings

What should I know before using Robitussin?

Before using this drug, tell your doctor if you are/have:

  • Pregnant or breastfeeding.
  • Taking any other medicines. This includes any prescription, OTC, and herbal remedies.
  • An allergy to any of the ingredients of this product.
  • Any other illnesses, disorders, or medical conditions.

Is it safe during pregnancy or breastfeeding?

Unfortunately, there isn’t enough information about the safety of using this drug during pregnancy and breastfeeding. However, it is likely safe to take. Please always consult with your doctor to weigh the potential benefits and risks before taking any medication.

Side Effects

What side effects can occur from Robitussin?

Like all drugs, this product may have side effects. If they occur, side effects are generally mild and resolve once treatment is finished or the dose is lowered. Some reported side effects include:

  • Nausea
  • Vomiting
  • Hypersensitivity

However, not everyone experiences these side effects. In addition, some people may experience other side effects. So, if you have any concerns about a side effect, please consult your doctor or pharmacist.


What drugs may interact with Robitussin?

This medication may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. 

To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist.

Does food or alcohol interact with Robitussin?

This drug may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Robitussin?

This drug may interact with underlying conditions. This interaction may worsen your health condition or alter the way the drug works. Therefore, it is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. Therefore, you should always consult with your doctor or pharmacist before using any medication.

What is the dose for an adult?

Take 1 to 2 capsules or 10 to 20 mL every 4 hours.

What is the dose for a child?

Based on age:

  • 12 years and above: Give 1 to 2 capsules or 10 to 20 mL every 4 hours.
  • 6 to 11 years: 1 capsule or 5 to 10 mL every 4 hours.
  • 2 to 5 years: 50 to 100 mg per dose, up to 600 mg per day.
  • Under 2 years: Do not give this drug.

How is Robitussin available?

Robitussin is available in the following dosage forms and strengths:

  • Oral syrup 100 mg/5 mL
  • Liquigel capsule 200 mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to the nearest emergency room.

What should I do if I miss a dose?

If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.


Hello Health Group does not provide medical advice, diagnosis or treatment.

Written by

Stephanie Nera, RPh, PharmD


Updated Jul 25, 2022

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