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Daflon (diosmin + hesperidin)

Written by Stephanie Nera, RPh, PharmD · Pharmacology

Updated May 26, 2021

Daflon is the brand name of a preparation that contains diosmin and hesperidin. This drug is a venotonic used to treat and prevent symptoms of venous circulation disorders. It is available as a film-coated tablet.


Know the basics

What is Daflon used for?

Daflon is commonly used for the treatment of symptoms related to venolymphatic insufficiency (heavy legs, pain, early morning restless legs) and treatment of functional symptoms related to the acute hemorrhoidal attack.

How should I take Daflon?

Should be taken with food and take at mealtimes.

How do I store Daflon?

This product is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store it in the bathroom or the freezer. There may be different brands that may have different storage needs. That is why it is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush this product down the toilet or pour them into a drain unless instructed to do so. Additionally, it is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Know the precautions & warnings

What should I know before using Daflon?

Before using this drug, consult with your doctor about:

  • Your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.)
  • You have allergies, pre-existing diseases, and current health conditions
  • Some health conditions may make you more susceptible to the side effects of the drug
  • You are pregnant and breastfeeding

Is it safe during pregnancy or breastfeeding?

Pregnancy: experimental studies in animals have not demonstrated any teratogenic effect in animals. Furthermore, no adverse effects have been reported to date in humans.

Lactation: in the absence of data concerning excretion into breast milk, breastfeeding is not recommended during treatment.

Know the side effects

What side effects can occur from Daflon?

Daflon is generally well-tolerated and side effects are rare. However, the most common side effects reported while using this drug include:

Not everyone experiences these side effects. Additionally, there may be other side effects not listed above. If you have any concerns about a side effect, please consult your doctor or pharmacist.

Know the interactions

What drugs may interact with Daflon?

Daflon may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects.

To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Daflon?

Daflon may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Daflon?

Daflon may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Understand the dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Daflon.

What is the dose for an adult?

  • Venous insufficiency: 1 tablet daily, by mouth
  • Hemorrhoidal attack: 3 tablets daily for four days then 2 tablets daily for three days. 

What is the dose for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Daflon available?

Daflon is available in the following dosage forms and strengths:

  • Film-coated tablet 500 mg, 1000 mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.


Hello Health Group does not provide medical advice, diagnosis or treatment.

Written by

Stephanie Nera, RPh, PharmD


Updated May 26, 2021

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