The information provided is not a substitute for any medical advice. Therefore, you should always consult with your doctor or pharmacist before using any medication.
What is the dose for an adult?
Usual Adult Dose for Congestive Heart Failure:
Initial dose: take 100 mg tablet orally twice a day. Double the dose at 2-4 weeks to the target dose of 200 mg twice a day as tolerated by the patient.
If the patient is not currently taking an ACE inhibitor or ARB: start at 50 mg twice a day and slow dose titration (doubling every 3 to 4 weeks).
For patients with systolic BP >100-110 mmHg, moderate to severe renal impairment, or moderate hepatic impairment (Child-Pugh B): starting dose is 50 mg taken twice a day.
What is the dose for a child?
The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.
How is Entresto available?
Entresto is available in the following dosage forms and strengths:
- Tablet, film-coated: 50 mg, 100 mg, 200 mg (each 50 mg contains sacubitril 24.3 mg + valsartan 25.7 mg)
What should I do in case of an emergency or overdose?
In case of an emergency or an overdose, call your local emergency services or go to the nearest emergency room. Signs and symptoms of an overdose or toxicity include:
- Low urine output
- Muscle weakness
- Loss of consciousness
What should I do if I miss a dose?
If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.