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Piascledine (unsaponifiable avocado and soybean oil)

Piascledine is the brand name of a product that contains unsaponifiable avocado oil and unsaponifiable soybean oil.

Studies have shown that these two oils have anti-inflammatory effects, prevent the breakdown of cartilage, and stimulates growth of joint cartilage cells (chondrocytes).

Piascledine

Uses

What is Piascledine used for?

According to the manufacturer, this drug eases symptoms of osteoarthritis. Other studies have shown that is also has effects against scleroderma and menopause symptoms.

How should I take Piascledine?

Read the directions on the packaging for complete information. Check the label and expiration date.

For oral dosage forms, swallow it whole without chewing, crushing, or dissolving it in liquid. Take it with plenty of water and meals to prevent gastric discomfort.

How do I store Piascledine?

This product is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store it in the bathroom or the freezer.

There may be different brands of this drug that may have different storage needs. So, it is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush this product down the toilet or pour them into a drain unless instructed to do so. Additionally, it is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Piascledine?

Before using this drug, tell your doctor if you are/have:

  • Pregnant or breastfeeding.
  • Taking any other medicines. This includes any prescription, OTC, and herbal remedies.
  • An allergy to any of the ingredients of this product.
  • Any other illnesses, disorders, or medical conditions.
  • On a fat-restricted diet or taking certain medications.

Is it safe during pregnancy or breastfeeding?

Unfortunately, there isn’t enough information about the safety of using this drug during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking any medication.

Side effects

What side effects can occur from Piascledine?

Like all drugs, this drug may have side effects. If they occur, side effects are generally mild and resolve once treatment is finished or the dose is lowered. Some reported side effects include:

  • Allergic reaction
  • Regurgitation
  • Gastrointestinal discomfort
  • Elevated liver enzymes

However, not everyone experiences these side effects. In addition, some people may experience other side effects. So, if you have any concerns about a side effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Piascledine?

This medication may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects.

To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist.

Does food or alcohol interact with Piascledine?

This drug may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Piascledine?

This drug may interact with underlying conditions. This interaction may worsen your health condition or alter the way the drug works. Therefore, it is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. Therefore, you should always consult with your doctor or pharmacist before using any medication.

What is the dose for an adult?

The recommended dose is one capsule per day with meals.

What is the dose for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is Piascledine available?

Piascledine is available in the following dosage forms and strengths:

  • Capsules containing unsaponifiable avocado oil 100 mg + unsaponifiable soybean oil 200 mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to the nearest emergency room.

What should I do if I miss a dose?

If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Piascledine https://www.mims.com/philippines/drug/info/piascledine Accessed July 23, 2021

Frequently asked questions https://www.piascledine.co.za/faq Accessed July 23, 2021

Management of Osteoarthritis with Avocado/Soybean Unsaponifiables https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303902/ Accessed July 23, 2021

Avocado–Soybean Unsaponifiables: A Panoply of Potentialities to Be Exploited https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023362/ Accessed July 23, 2021

Piascledine. Lexi-Drugs. Lexicomp. Wolters Kluwer Health, Inc. Riverwoods, IL. Accessed July 23, 2021. http://online.lexi.com

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Written by Stephanie Nicole Nera, RPh, PharmD Updated just now
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