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Fusidic acid is prescribed for skin infections caused by staphylococcal bacteria. Such infections include impetigo, angular cheilitis (an infection around the mouth), and infected dermatitis. It works by stopping the growth of the bacteria causing the infection. Sodium fusidate is a salt of fusidic acid and it works in the same way. You may find this name being given as the ingredient if you have been prescribed an ointment to use.
Fusidic acid cream and sodium fusidate ointment are antibacterial preparations which usually clear skin infection quickly, particularly where the infection only covers a small area. If the infection is more widespread, antibiotic tablets or a liquid medicine may be needed (see separate medicine leaflet called Sodium fusidate for infections for more information about this). This drug is also available as an oral antibiotic.
If the area of skin is inflamed as well as infected, your doctor may prescribe a cream which combines fusidic acid with an anti-inflammatory agent, such as hydrocortisone (brand name Fucidin® H) or betamethasone (brand name Fucibet®).
Before you start this treatment, read the manufacturer’s printed information leaflet from inside your pack. The leaflet will give you more information about the cream or ointment, and how to use it.
Use the preparation exactly as your doctor tells you to. Apply a thin layer of cream/ointment to the infected area and rub it in gently. Unless you have been told otherwise, use it 3-4 times a day. Remember to wash your hands well after you have finished using it (unless you are using it to treat your hands).
Only use it for as long as your doctor has instructed you to. A course of treatment for impetigo typically lasts for around 7-10 days.
Fusidic acid is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store fusidic acid in the bathroom or the freezer. There may be different brands of fusidic acid that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.
You should not flush fusidic acid down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.
Before taking this medication, tell your doctor if you:
There isn’t enough information about the safety of using this medication during pregnancy and breast-feeding. Please always consult with your doctor to weigh the potential benefits and risks before taking this medication.
Fusidic acid eye drops:
Fusidic acid cream:
Fusidic acid suspension:
If any of these persist or you consider them severe then you should inform your doctor or pharmacist.
Tell your doctor immediately if you develop any of the following symptoms while you are using fusidic acid eye drops or cream:
Tell your doctor immediately if you develop any of the following symptoms while you are using fusidic acid suspension:
A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), dizziness, trouble breathing.
Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.
Fusidic acid may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.
Using fusidic acid with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Fusidic acid may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. If you are taking the oral form of this drug, it is recommended to take it along with food. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.
Fusidic acid may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have, especially:
The information provided is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist before using this medication.
Adult: 500 mg orally three times a day. May increase to 1 g three times a day in fulminating infections.
Adult: greater than 50 kg: 500 mg three times a day; may increase to 1 g three times a day in fulminating infections. Greater than 50 kg: 6-7 mg/kg three times a day. To be given by slow intravenous infusion over at least 2 hr; should be given via a large vein with good blood flow.
Adult: As 1% eye drops, ophthalmic: Instill 1 drop into the affected eye every 12 hr for 7 days.
Adult: As a 2% ointment/cream/gel, Topical/Cutaneous: Apply onto affected area 3-4 times daily until there is improvement. If gauze dressing is used, then frequency of application may be reduced to 1-2 times daily.
Reconstitution: Each 500 mg dose is given as a buffered solution (pH 7.4-7.6) diluted to 500 ml with sodium chloride or other suitable IV solution.
Incompatibility: Incompatible with amino acid solutions or whole blood. Admixture incompatibility: Carbenicillin, kanamycin, gentamicin, calcium solutions.
Child: less than 1 year: orally, About 15 mg/kg; 1-5 year: 250 mg; 5-12 year: 500 mg. Doses to be taken three times a day.
Child: 20 mg/kg intravenous daily in 3 divided doses. To be given by slow intravenous infusion over at least 2 hr; should be given via a large vein with good blood flow.
Child: ≥2 yr: As 1% eye drops, ophthalmic: Instill 1 drop into the affected eye every 12 hr for 7 days.
Child: As a 2% ointment/cream/gel, Topical/Cutaneous: Apply onto affected area 3-4 times daily until there is improvement. If gauze dressing is used, then frequency of application may be reduced to 1-2 times daily.
Fusidic acid is available in the following dosage forms and strengths:
Each 5ml of Suspension contains 250mg Fusidic Acid, Ph.Eur. (therapeutically equivalent to 175mg Sodium Fusidate
Fucidin suspension contains 2mg sodium in every 1ml).
Fusidic Acid 20mg/g Cream
Fucidin Tablet: 250 mg
Fucidin Powder for Injection: 500 mg
In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.
If you miss a dose of fusidic acid, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.
Hello Health Group does not provide medical advice, diagnosis or treatment.
Fusidic Acid http://drugs.webmd.boots.com/drugs/drug-217- Fusidic+Acid.aspx. Accessed July 16, 2016.
Fusidic Acid http://www.medbroadcast.com/Drug/GetDrug/Fucidin-Cream. Accessed July 16, 2016.
Fusidic Acid oral route injection route http://www.mayoclinic.org/drugs-supplements/fusidic- acid-oral- route-injection-route/description/drg-20067601. Accessed July 16, 2016.