Are you sure you want to log out?
Please tell us what was incorrect.
Please tell us what was missing.
We’re unable to offer personal health advice, diagnosis, or treatment, but we welcome your feedback! Just type it in the box below.
This drug or supplement is not currently available for sale or use in the Philippines. The information provided here is for informational purposes only.
Rantudil® (acemetacin) is a nonsteroidal anti-inflammatory drug (NSAID), specifically a non-selective cyclooxygenase (COX) inhibitor. NSAIDs treat various causes of pain, inflammation, and swelling. It can also aid in reducing fever.
COX inhibitors block the action of either or both the COX-1 and COX-1 enzymes. These enzymes convert arachidonic acid into prostaglandin, which is a group of substances that regulate many cellular processes such as platelet aggregation, vasodilation, gastric mucus secretion, and proinflammatory mediators.
Acemetacin is derived from indomethacin, another NSAID. It has less gastric irritating effects than indomethacin.
Rantudil is mainly indicated to treat the following conditions:
Rantudil and Rantudil Retard are available as oral capsules. The oral capsules should be swallowed whole without chewing or crushing them. They should be taken with food to prevent gastric irritation.
This drug should be stored at room temperature (<30°C) and be protected from light and moisture. Do not store it in the refrigerator or freezer. For safety, keep out of the reach of children and pets.
Always check the label before using this product. Do not use if the printed expiration date has passed, the product seal has been broken, or the product has changed in color, odor, or consistency.
Do not dispose of this product by pouring it down the drain, toilet, or into the environment. Ask your pharmacist regarding the proper way and location of disposal.
NSAIDs, including Rantudil, are associated with an increased risk of bleeding and gastric ulceration. This risk is further increased in older patients usually over 60 years of age, those taking blood thinners, and those with blood clotting disorders.
Some groups of people with conditions like asthma or allergic rhinitis may experience an exacerbation of symptoms after using NSAIDs.
Before using this medication, inform your doctor if:
This drug is not recommended for use during pregnancy and is contraindicated for use during the 3rd trimester. This drug should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus, as determined by your doctor.
This drug may be excreted in breast milk. This drug should be used while breastfeeding only if the potential benefit justifies the potential risk to the child, as determined by your doctor.
All drugs can elicit side effects even with normal use. Most side effects are dose-related and will resolve when it is adjusted or at the end of therapy.
Potential side effects while using this drug include:
Seek medical attention immediately if you experience any of these serious, potentially fatal drug reactions:
You may experience some, none, or other side effects not mentioned above. If you have any concerns about a side effect or it becomes bothersome, consult your doctor or pharmacist.
This drug may interact with other medications. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and inform your doctor and pharmacist.
Known drugs and their interactions with Rantudil include:
If you experience an adverse drug interaction, stop taking this drug and continue taking your other medication. Inform your doctor immediately to reevaluate your treatment plan. Your dose may need to be adjusted, substituted with another drug, or discontinue using the drug.
Food has no notable effects on Rantudil, however, it is best to take it with meals to prevent gastric irritation. This drug should not be taken with alcohol as it may increase the risk of gastrointestinal ulceration, bleeding, and hepatotoxicity.
Inform your doctor or pharmacist if you have any concerns regarding food-drug interactions.
This drug should be taken with caution if you have any of the following conditions or risk factors:
Inform your doctor or pharmacist if you have any concerns regarding specific health conditions.
The information provided is not a substitute for any medical advice. You should ALWAYS consult your doctor or pharmacist before using Rantudil.
For pain, inflammation, musculoskeletal and joint disorders
Dose adjustments for elderly patients
This drug is not recommended for use in children and the recommended dose has not been established. Consult with a doctor or pharmacist for alternatives and more information.
This drug is available in the following formulations, dosage forms, and strengths:
In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.
What should I do if I miss a dose?
If you miss a dose of this drug, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.
Hello Health Group does not provide medical advice, diagnosis or treatment.
Rantudil®, https://www.mims.com/philippines/drug/info/rantudil-rantudil%20retard, Accessed Aug 20, 2020
Acemetacin, https://www.mims.com/philippines/drug/info/acemetacin?mtype=generic, Accessed Aug 20, 2020
Acemetacin, https://pubchem.ncbi.nlm.nih.gov/compound/Acemetacin, Accessed Aug 20, 2020