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Know the basics|Know the precautions & warnings|Know the side effects|Know the interactions|Understand the dosage

Know the basics

What is felodipine used for?

Felodipine is known as a calcium channel blocker.

Felodipine is used to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. By blocking calcium, this medication relaxes and widens blood vessels so blood can flow more easily.

OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by yourhealth care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.

Felodipine may also be used to prevent chest pain (angina).

How should I take felodipine?

Take felodipine by mouth usually once a day on an empty stomach, or as directed by your doctor. If stomach upset occurs, felodipine may be taken with a light meal. Dosage is based on your medical condition and response to therapy.

Do not crush or chew extended-release tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.

Use felodipine regularly in order to get the most benefit from it. Remember to use it at the same time each day as directed. It is important to continue taking felodipine even if you feel well. Most people with high blood pressure do not feel sick.

This drug is not effective if you use it only when chest pain occurs. It is very important to take felodipine regularly as prescribed to help prevent chest pain.

Avoid eating grapefruit or drinking grapefruit juice while being treated with felodipine unless your doctor instructs you otherwise. Grapefruit juice can increase the amount of felodipine in your bloodstream. Consult your doctor or pharmacist for more details.

Do not stop taking felodipine without consulting your doctor. Some conditions may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased.

How do I store felodipine?

Felodipine is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store felodipine in the bathroom or the freezer. There may be different brands of felodipine that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush felodipine down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Know the precautions & warnings

What should I know before using felodipine?

Before taking felodipine,

  • Tell your doctor and pharmacist if you are allergic to felodipine or any other drugs.
  • Tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially antiseizure medicines such as carbamazepine (tegretol), phenytoin (dilantin), and phenobarbital; cimetidine (tagamet); erythromycin (e.e.s., e-mycin, others); itraconazole (sporanox); ketoconazole (nizoral); ranitidine (zantac); and vitamins.
  • Tell your doctor if you have or have ever had heart, liver, or kidney disease.
  • Tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking felodipine, call your doctor.
  • If you are having surgery, including dental surgery, tell your doctor or dentist that you take felodipine.

Is it safe to take felodipine during pregnancy or breast-feeding?

There are no adequate studies in women for determining risk when using felodipine during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking felodipine. Felodipine is pregnancy risk category C according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk,
  • B=No risk in some studies,
  • C=There may be some risk,
  • D=Positive evidence of risk,
  • X=Contraindicated,
  • N=Unknown

Know the side effects

What are the side effects of felodipine?

Common side effects include dizziness, lightheadedness, headache, flushing, or stomach upset as your body adjusts to the medication.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as: feeling like you might pass out; feeling short of breath, swelling in your hands or feet; fast or pounding heartbeats; numbness or tingly feeling; or chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling.

Less serious side effects may include: headache, dizziness, drowsiness, weakness; feeling restless or nervous; nausea, upset stomach, constipation, diarrhea, stomach pain; sleep problems (insomnia); joint pain or muscle cramps; warmth, redness, or tingly feeling under your skin; mild rash; urinating more than usual; or cold symptoms such as stuffy nose, sneezing, sore throat

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Know the interactions

What drugs may interact with felodipine?

Felodipine may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with Colchicine, Itraconazole, Ketoconazole is not recommended. Your doctor may decide not to treat you with felodipine or change some of the other medicines you take:

Using felodipine with any of the following medicines is usually not recommended, but may be required in some cases: Afatinib; Amiodarone; Atazanavir; Bosutinib; Carbamazepine; Ceritinib; Clarithromycin; Clopidogrel; Cobicistat; Cyclosporine; Dabigatran Etexilate; Dabrafenib; Dantrolene; Doxorubicin; Doxorubicin Hydrochloride Liposome; Droperidol; Eslicarbazepine Acetate; Everolimus; Idelalisib; Lacosamide; Mibefradil; Mitotane; Morphine; Morphine Sulfate Liposome; Nilotinib; Piperaquine; Pixantrone; Pomalidomide; Primidone; Romidepsin; Siltuximab; St John’s Wort; Topotecan; Trabectedin; Vincristine; Vincristine Sulfate Liposome. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you: Acebutolol; Aceclofenac; Acemetacin; Alprenolol; Amprenavir; Amtolmetin Guacil; Aspirin; Atenolol; Betaxolol; Bevantolol; Bisoprolol; Bromfenac; Bucindolol; Bufexamac; Carteolol; Carvedilol; Celecoxib; Celiprolol; Choline Salicylate; Clonixin; Dalfopristin; Dexibuprofen; Dexketoprofen; Diclofenac; Diflunisal; Dilevalol; Dipyrone; Esmolol; Etodolac; Etofenamate; Etoricoxib; Felbinac; Fenoprofen; Fepradinol; Feprazone; Floctafenine; Fluconazole; Flufenamic Acid; Flurbiprofen; Ibuprofen; Ibuprofen Lysine; Indinavir; Indomethacin; Ketoprofen; Ketorolac; Labetalol; Levobunolol; Lornoxicam; Loxoprofen; Lumiracoxib; Magnesium; Meclofenamate; Mefenamic Acid; Meloxicam; Mepindolol; Metipranolol; Metoprolol; Morniflumate; Nabumetone; Nadolol; Naproxen; Nebivolol; Nelfinavir; Nepafenac; Niflumic Acid; Nimesulide; Oxaprozin; Oxcarbazepine; Oxprenolol; Oxyphenbutazone; Parecoxib; Penbutolol; Phenobarbital; Phenylbutazone; Piketoprofen; Pindolol; Piroxicam; Pranoprofen; Proglumetacin; Propranolol; Propyphenazone; Proquazone; Quinupristin; Rifapentine; Rofecoxib; Salicylic Acid; Salsalate; Sodium Salicylate; Sotalol; Sulindac; Talinolol; Tenoxicam; Tertatolol; Tiaprofenic Acid; Timolol; Tolfenamic Acid; Tolmetin; Valdecoxib. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Does food or alcohol interact with felodipine?

Felodipine may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug, especially Grapefruit Juice.

What health conditions may interact with felodipine?

Felodipine may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have, especially:

  • Heart failure—Use with caution. May make this condition worse.
  • Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Understand the dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using felodipine.

What is the dose of felodipine for an adult?

Usual Adult Dose for Hypertension

  • Initially, 5 mg daily. Individualised dose may be adjusted based on patient response. Usual dose: 2.5-10 mg daily.

Usual Geriatric Dose for Hypertension

  • Initially, 2.5 mg daily. Monitor blood pressure during titration.

Usual Adult Dose for Angina Pectoris

  • Initially, 5 mg daily, may increase to 10 mg daily as necessary.

Usual Geriatric Dose for Angina Pectoris

  • Initially, 2.5 mg daily.

What is the dose of felodipine for a child?

Usual Pediatric Dose for Hypertension:

Felofipine is not approved by FDA for usual pediatric treatment for Hypertension.

How is felodipine available?

Felodipine is available in the following dosage forms and strengths:

Tablet, oral: 5 mg, 10 mg

Tablet modified release, oral: 5 mg

Tablet Extended Release 24 Hour, Oral: 2.5 mg, 5 mg, 10 mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services (115) or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of felodipine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Picture of the author
Written by Stephanie Nicole Nera, RPh, PharmD on May 02, 2020
Medically reviewed by Stephanie Nicole Nera, RPh, PharmD