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Felodipine (antihypertensive agent)

Know the basics|Know the precautions & warnings|Know the side effects|Know the interactions|Understand the dosage

Felodipine is a generic drug known as a calcium channel blocker. By blocking calcium, this medication relaxes and widens blood vessels so blood can flow more easily. It is an antihypertensive medication.

felodipine

Know the basics

What is felodipine used for?

Felodipine treats high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.

Felodipine may also be used to prevent chest pain (angina).

How should I take felodipine?

Read the directions on the packaging for complete information. Check the label and expiration date.

Swallow the tablet whole without chewing or crushing it. Take it with or without meals.

How do I store felodipine?

This product is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store it in the bathroom or the freezer.

There may be different brands of this drug that may have different storage needs. So, it is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush this product down the toilet or pour them into a drain unless instructed to do so. Additionally, it is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Know the precautions & warnings

What should I know before using felodipine?

Before using this drug, tell your doctor if you are/have:

  • Pregnant or breastfeeding.
  • Taking any other medicines. This includes any prescription, OTC, and herbal remedies.
  • An allergy to any of the ingredients of this product.
  • Any other illnesses, disorders, or medical conditions.

Is it safe to take felodipine during pregnancy or breastfeeding?

Unfortunately, there isn’t enough information about the safety of using this drug during pregnancy and breastfeeding. However, it is likely safe to take. Please always consult with your doctor to weigh the potential benefits and risks before taking any medication.

This medication is pregnancy risk category C according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Know the side effects

What are the side effects of felodipine?

Like all drugs, this product may have side effects. If they occur, side effects are generally mild and resolve once treatment is finished or the dose is lowered. Some reported side effects include:

  • Palpitations
  • Headache
  • Dizziness
  • Nausea, vomiting
  • Gingival hyperplasia
  • Fatigue
  • Increased liver enzymes
  • Flushing

Seek medical attention if you experience any severe or significant reactions such as:

  • Tachycardia
  • Heart attack (myocardial infarction)
  • Peripheral edema (swelling)
  • Angina
  • Hypotension
  • Fainting (syncope)

However, not everyone experiences these side effects. In addition, some people may experience other side effects. So, if you have any concerns about a side effect, please consult your doctor or pharmacist.

Know the interactions

What drugs may interact with felodipine?

This medication may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects.

To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist.

Drugs with known interactions:

  • Cimetidine
  • Erythromycin
  • Itraconazole
  • Ritonavir
  • Phenytoin
  • Carbamazepine
  • Rifampicin
  • Barbiturates
  • Tacrolimus
  • St. John’s wort

If you experience an adverse drug interaction, stop taking this drug and continue taking your other medication. Inform your doctor immediately to reevaluate your treatment plan. Approaches include dose adjustment, drug substitution, or ending therapy.

Does food or alcohol interact with felodipine?

This drug may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Avoid taking this medication with high fat meals or with grapefruit. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with felodipine?

This drug may interact with underlying conditions. This interaction may worsen your health condition or alter the way the drug works. Therefore, it is important to always let your doctor and pharmacist know all the health conditions you currently have, especially:

  • Heart disease
  • Liver disease

Understand the dosage

The information provided is not a substitute for any medical advice. Therefore, you should always consult with your doctor or pharmacist before using any medication.

What is the dose for an adult?

Hypertension

  • Initially, 5 mg daily. Individualised dose may be adjusted based on patient response. Usual dose: 2.5-10 mg daily.

Hypertension

  • Initially, 2.5 mg daily. Monitor blood pressure during titration.

Angina Pectoris

  • Initially, 5 mg daily, may increase to 10 mg daily as necessary.

Angina Pectoris

  • Initially, 2.5 mg daily.

What is the dose for a child?

There is no established pediatric dose. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is felodipine available?

Felodipine is available in the following dosage forms and strengths:

Oral tablet: 5 mg, 10 mg

Modified-release tablet: 5 mg

Extended-release tablet: 2.5 mg, 5 mg, 10 mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to the nearest emergency room.

What should I do if I miss a dose?

If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Sources

Felodipine https://www.mims.com/philippines/drug/info/felodipine?mtype=generic Accessed June 22, 2021

Felodipine https://www.nhs.uk/medicines/felodipine/ Accessed June 22, 2021

Felodipine (Oral Route) https://www.mayoclinic.org/drugs-supplements/felodipine-oral-route/side-effects/drg-20071701?p=1 Accessed June 22, 2021

Felodipine https://www.ncbi.nlm.nih.gov/books/NBK542163/ Accessed June 22, 2021

Felodipine. Lexi-Drugs. Lexicomp. Wolters Kluwer Health, Inc. Riverwoods, IL. Accessed June 22, 2021. http://online.lexi.com

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Written by Stephanie Nicole Nera, RPh, PharmD Updated Jun 22
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