Are you sure you want to log out?
Please tell us what was incorrect.
Please tell us what was missing.
We’re unable to offer personal health advice, diagnosis, or treatment, but we welcome your feedback! Just type it in the box below.
Glibenclamide or glyburide is part of a class of drugs known as antidiabetics, specifically a sulfonylurea. It is used in type 2 diabetes mellitus when your blood sugar cannot be controlled through diet and lifestyle modification alone.
Glibenclamide is available as an oral tablet. The oral tablet should be taken by mouth without chewing or crushing it. The tablets can be taken with a meal, ideally breakfast.
This drug should be stored at room temperature (<30°C) and be protected from light and moisture. For safety, keep out of the reach of children and pets.
Always check the label before using this product. Do not use if the printed expiration date has passed, the product seal has been broken, or the product has changed in color, odor, or consistency.
Do not dispose of this product by pouring it down the drain, toilet, or into the environment. Ask your pharmacist regarding the proper way and location of disposal.
Sulfonylureas, including glibenclamide, are associated with an increased risk of hypoglycemia. This risk is further increased in older patients usually over 60 years of age, regular alcohol drinkers, and those with metabolic conditions.
Before using this medication, inform your doctor if:
This drug is a pregnancy category C drug. There have not been any studies done on pregnant women to determine if glibenclamide causes fetal harm. This drug should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus, as determined by your doctor.
This drug may be excreted in breast milk. It may alter the composition or quality of breast milk. This drug should be used while breastfeeding only if the potential benefit justifies the potential risk to the child, as determined by your doctor.
All drugs have the potential to elicit side effects even with normal use. Many side effects are dose-related and will resolve when it is adjusted or at the end of therapy.
Potential side effects while using this drug include:
Seek medical attention immediately if you experience any of these serious, potentially fatal drug reactions:
You may experience some, none, or other side effects not mentioned above. If you have any concerns about a side effect or it becomes bothersome, consult your doctor or pharmacist.
This drug may interact with other medications. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and inform your doctor and pharmacist.
Known drugs and their interactions with glibenclamide include:
If you experience an adverse drug interaction, stop taking this drug and continue taking your other medication. Inform your doctor immediately to reevaluate your treatment plan. Your dose may need to be adjusted, substituted with another drug, or discontinue using the drug.
There are no notable interactions with food. This drug should not be taken with alcohol as it may increase the severity of hypoglycemia and cause disulfiram-like reactions.
Inform your doctor or pharmacist if you have any concerns regarding food-drug interactions.
This drug should be taken with caution if you have any of the following conditions or risk factors:
Inform your doctor or pharmacist if you have any concerns regarding specific health conditions.
The information provided is not a substitute for any medical advice. You should ALWAYS consult your doctor or pharmacist before using glibenclamide.
For type 2 diabetes mellitus
This drug is not recommended for use in children and the recommended dose has not been established. Consult with a doctor or pharmacist for alternatives and more information.
This drug is available in the following dosage forms and strengths:
In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.
If you miss a dose of this drug, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.
Hello Health Group does not provide medical advice, diagnosis or treatment.
Glibenclamide, https://www.mims.com/philippines/drug/info/glibenclamide?mtype=generic, Accessed Aug 31, 2020
Glibenclamide, https://medicalguidelines.msf.org/viewport/EssDr/english/glibenclamide-oral-16683809.html, Accessed Aug 31, 2020