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Erenumab (monoclonal antibody, anti-migraine agent)

Uses|Precautions & warnings|Side effects|Interactions|Dosage

Erenumab is a monoclonal antibody drug. It works by blocking calcitonin gene-related peptide receptors and is indicated for the preventive treatment of migraine in adults.



What is erenumab used for?

Prophylaxis of frequent migraines in adults.

How should I take erenumab?

Read the directions on the packaging for complete information. Check the label and expiration date.

For parenteral dosage forms, only a licensed healthcare professional should administer it. Do not shake the vial.

How do I store erenumab?

Store this product in a refrigerator (2-8°C) away from direct light and moisture. Do not shake the vial. To prevent drug damage, you should not store it in the bathroom or the freezer.

There may be different brands of this drug that may have different storage needs. So, it is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush this product down the toilet or pour them into a drain unless instructed to do so. Additionally, it is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using erenumab?

Before using this drug, tell your doctor if you are/have:

  • Pregnant or breastfeeding.
  • Taking any other medicines. This includes any prescription, OTC, and herbal remedies.
  • An allergy to any of the ingredients of this product.
  • Any other illnesses, disorders, or medical conditions.

Is it safe during pregnancy or breast-feeding?

Unfortunately, there isn’t enough information about the safety of using this drug during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking any medication.

This medication is pregnancy risk category N according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A= No risk
  • B= No risk in some studies
  • C= There may be some risk
  • D= Positive evidence of risk
  • X= Contraindicated
  • N= Unknown

Side effects

What side effects can occur from erenumab?

Like all drugs, this product may have side effects. If they occur, side effects are generally mild and resolve once treatment is finished or the dose is lowered. Some reported side effects include:

  • Injection site reactions
  • Constipation
  • Antibody development
  • Muscle cramps and spasms
  • Hypertension
  • Hair loss
  • Skin rash
  • Oral mucosa ulcer
  • Angioedema
  • Hypersensitivity reactions

However, not everyone experiences these side effects. In addition, some people may experience other side effects. So, if you have any concerns about a side effect, please consult your doctor or pharmacist.


What drugs may interact with erenumab?

This medication may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects.

To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist.

Does food or alcohol interact with Erenumab?

This drug may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Erenumab?

This drug may interact with underlying conditions. This interaction may worsen your health condition or alter the way the drug works. Therefore, it is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. Therefore, you should always consult with your doctor or pharmacist before using any medication.

What is the dose for an adult?

Migraine Prophylaxis

Administer 70 mg via subcutaneous injection, once a month.

Some patients may benefit from a dosage of 140 mg subcutaneously, once a month.

A dose of 140 mg should be administered as 2 consecutive subcutaneous injections of 70 mg each.

What is the dose for a child?

There is no established pediatric dose. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is erenumab available?

Erenumab is available in the following brands, dosage forms, and strengths:

  • Aimovig SureClick® Autoinjector 70 mg/mL, 140 mg/mL
  • Aimovig Prefilled Syringe 70 mg/mL, 140 mg/mL

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to the nearest emergency room.

What should I do if I miss a dose?

If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.


Erenumab https://www.mims.com/philippines/drug/info/erenumab?mtype=generic Accessed July 5, 2021

The role of erenumab in the treatment of migraine
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7257830/ Accessed July 5, 2021

Erenumab (Aimovig) for Migraine Prophylaxis in Adults https://www.aafp.org/afp/2019/0615/p781.html Accessed July 5, 2021

Erenumab for migraine https://www.nps.org.au/australian-prescriber/articles/erenumab-for-migraine Accessed July 5, 2021

Erenumab. Lexi-Drugs. Lexicomp. Wolters Kluwer Health, Inc. Riverwoods, IL. Accessed July 5, 2021. http://online.lexi.com

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Written by Stephanie Nicole Nera, RPh, PharmD Updated 4 weeks ago