In some cases, oral medications for diabetes are not enough or lose effectiveness. Some doctors initiate insulin monotherapy wherein the treatment will require insulin alone and will stop the oral medication.
In a later stage, oral agents may be taken alongside insulin if the blood sugar failed to achieve its average level. In the combination of insulin and oral medication, the insulin dosage may reduce and decrease the side effects due to insulin. However, other side effects of the oral agents might also occur.
Other treatment options also include bariatric surgery, artificial pancreas, and pancreatic islet transplantation. These are the less common treatments available when medicines are not enough to control the condition.
Bariatric surgery is an option for obese patients with diabetes, which can help them lose weight and decrease food intake. Because type 1 diabetes is caused by damaged or missing pancreas cells that produce insulin, some patients can benefit from a pancreas transplant or artificial pancreas.