Not to be confused with diabetes mellitus, diabetes insipidus happens when the kidney is unable to control the amount of water in the urine during the filtering process.
Apart from extreme dehydration, diabetes insipidus can bring forth other illnesses, if not managed properly. Read on to know about diabetes insipidus causes, signs and symptoms, as well treatment options available.
What are diabetes insipidus causes?
Diabetes insipidus is the failure of the kidneys to control water balance, leading to frequent urination. The main culprit behind this is a chemical known as vasopressin (AVP) or the antidiuretic hormone (ADH).
This chemical can be found in the hypothalamus, and is stored in the pituitary gland. This chemical is responsible for regulating the water found in the urine. Think of it this way: When you’re thirsty, the pituitary gland sends AVP to help conserve water, and temporarily halt the production of urine.
The opposite happens when you have diabetes insipidus. It’s either there isn’t enough AVP or the kidney fails to respond properly to the chemical.
Diabetes insipidus causes can also depend on the type of disease you have:
Cranial diabetes insipidus
If somehow your pituitary gland or hypothalamus got affected by a recent surgery, trauma, or illness, this can affect the production of AVP. There are cases where an inherited genetic disease can cause this type of diabetes insipidus.
Nephrogenic diabetes insipidus
This occurs when there is a defect in the kidney structures due to a disorder or reaction to a medication that prevents it from responding to AVP.