What is Early Pregnancy Loss?
The most common complication of pregnancy is early pregnancy loss or miscarriage. It is the loss of a pregnancy due to natural causes during the first 13 weeks of pregnancy. Despite the fact that 15% of clinically recognized pregnancies end in miscarriage, total reproductive losses are closer to 50%. Sporadic and recurrent miscarriage are the two types of miscarriage.
It has been discovered that at least 25% of all women, and maybe as many as 50%, have one or more sporadic miscarriages, which are usually caused by random fetal chromosomal abnormalities, and the chance of which increases with maternal age. Recurrent miscarriage, on the other hand, is a less common occurrence, affecting only 1% of couples.
This occurs when a pregnancy is lost three or more times in a row. It’s one of a group of reproductive illnesses that all have the same underlying etiology.
Recurrent miscarriage is defined by many clinicians as two or more losses; this increases the prevalence of the problem from 1% to 5% of all couples trying to conceive.
Recurrent miscarriage has several characteristics. First, a woman’s chance of miscarriage is linked to her past pregnancies’ outcomes. Second, the observed rate of recurrent miscarriage (1%) is significantly higher than what would be expected by chance (0.34%). Recurrent miscarriage, unlike sporadic miscarriage, occurs even when the fetus has a normal chromosomal complement. Finally, recurrent miscarriage is more common in women who have certain reproductive traits.
Is there a link between PCOS and recurrent early miscarriage?
Causes of Recurrent Miscarriage
Historically, recurrent miscarriage has been found to be caused by the following:
The most common cause of miscarriage during 10 weeks of pregnancy happens when the fetus has one or more extra or missing chromosomes. At least half of all miscarriages are caused by cytogenetic abnormalities.
Recurrent miscarriage may make certain women more susceptible to heterotrisomy, or the recurrence of a different trisomy after a trisomic pregnancy.
Couples with a history of recurrent miscarriage who had in-vitro fertilization had more defective embryos than couples without a history of recurrent miscarriage, according to one screening research.