Aside from the hormones which could be the main cause of myoma, genetics also seem to play a significant role. This means that some women are more predisposed to have uterine fibroid growths than others.
Various studies determined that:
- Uterine fibroids appear to be hereditary. If you have relatives with myoma, you are at a higher risk of developing it, too. In fact, a woman whose mother had uterine fibroids is 3 times more likely to have benign growths as well.
- Myoma is also associated with mutations or changes in the following genes: MED12, HMGA, FH, and COL4A5/COL4A6.
- These genes perform various functions such as protein synthesis, gene expression tuning, enzyme-making, and collagen formation.
Aside from genes, it seems like ethnicity or race may also cause myoma to grow. According to reports, uterine fibroids are most common among women of the black race. On the other hand, the occurrences seem to be rarest among women in the Asian race.
Certain reproductive factors may also determine if a woman will develop uterine fibroids. Consider the following findings:
- There is an inverse relationship between parity and myoma risk. What it means is that a woman who has given birth at least once is less likely to have uterine fibroids.
- The risk further decreases the more number of children a woman has.
- Researchers also noted that an increasing number of term pregnancies decreases the risk of uterine fibroid development.
- Due to this, experts explain that myoma is most common among “nulliparous” women or those who haven’t had a child yet.
Diet and Lifestyle
If hormones are considered the main cause of myoma, several aspects of a person’s diet and lifestyle could be contributing factors.
- Excess Weight and Obesity. Some studies reveal that obesity could increase the risk of developing uterine fibroids. It’s even possible that obesity could “lessen” the inverse relationship between parity and myoma risk.
- Diet. Certain factors in a woman’s diet could also cause myoma to grow. For instance, eating too much meat could heighten uterine fibroid growth. On the other hand, a diet rich in fruits and vegetables seems to reduce the risk.
- Alcohol Consumption. A Japanese study found a strong correlation between alcohol consumption and fibroid risk. In another study, the investigators revealed that the association is “stronger” with beer consumption than wine intake.
- Micronutrient deficiency. Some micronutrients may also affect the development of myoma. For instance, one study found out that Vitamin D deficiency is associated with uterine fibroid growths.
- Stress. While there are very few studies about stress and fibroid risk, some researchers believe that it could also be a potential risk factor.
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