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Update Date 03/12/2020 . 5 mins read
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What is Sterilid-V used for?

Sterilid-V is a combination preparation of two drugs: sulfacetamide sodium and prednisolone acetate. It is used to treat eye conditions that require preventing infection as well as inflammation and redness. It is available as an ophthalmic suspension in the form of eye drops.

Sulfacetamide sodium is an antibacterial under the class of drugs called sulfonamides. It is bacteriostatic, which means it prevents the growth of bacteria but does not necessarily kill bacteria upon exposure. The coverage of sulfacetamide includes susceptible strains of:

  • Escherichia coli
  • Staphylococcus aureus
  • Streptococcus pneumoniae
  • Viridans streptococci
  • Haemophilus influenzae
  • Klebsiella spp
  • Enterobacter spp

Prednisolone is part of a class of drugs known as corticosteroids. Corticosteroids, or steroids, are synthetic drugs that are modeled after the naturally occurring hormone cortisol, which is produced in the adrenal glands. Corticosteroids are used to reduce inflammation, pain, itchiness, and other effects mediated by the immune system response.

Sterilid-V is mainly indicated to treat the symptoms of the following conditions:

  • Palpebral and bulbar conjunctiva
  • Allergic conjunctivitis
  • Superficial punctate keratitis
  • Trachoma

How should I take Sterilid-V?

Sterilid-V is available as a topical ointment, lotion, cream, and parenteral suspension for injection. The topical dosage forms should be applied as a thin layer on the affected areas of skin. Wash your hands thoroughly before and after application.

The suspension for injection should be administered via intramuscular (IM), intralesional, or intra-articular (IA) routes by a licensed health professional.

How do I store Sterilid-V?

This drug should be stored at controlled room temperature (8-25°C) and be protected from light and moisture. Always check the label before using this product. For safety, keep out of the reach of children and pets.

Do not use if the printed expiration date has passed, the product seal has been broken, or the product has changed in color, odor, or consistency.

Do not dispose of this product by pouring it down the drain, toilet, or into the environment. Ask your pharmacist regarding the proper way and location of disposal.

Precautions & warnings

What should I know before using Sterilid-V?

Corticosteroids, including Sterilid-V, are associated with an increased risk of infection, bone demineralization, weight gain, water retention, and various other effects. This risk is further increased in elderly patients, young patients, immunocompromised patients, and those undergoing chronic treatment with steroids.

Never stop taking corticosteroids suddenly. If side effects are being experienced or you have completed your therapy, your doses must be tapered gradually until it is safe to stop taking corticosteroids. Abruptly stopping the use of steroids can result in adrenal insufficiency, which is potentially life-threatening.

Some groups of people with conditions like osteoporosis, diabetes mellitus, hypertension, hypothyroidism, myopathy, glaucoma, and myasthenia gravis may experience an exacerbation of symptoms after using corticosteroids.

Before using this medication, inform your doctor if:

  • You have ever had an allergic reaction to Sterilid-V or other corticosteroids
  • You have a history of allergy to other medications, food, or other substances
  • You are taking other medications, especially other corticosteroids
  • You have underlying health conditions

Is it safe during pregnancy or breastfeeding?

This drug is a pregnancy category C drug. There is insufficient evidence from human studies that shows it can cause fetal harm when taken during pregnancy. This drug should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus, as determined by your doctor.

This drug may be excreted in breast milk. This drug should be used while breastfeeding only if the potential benefit justifies the potential risk to the child, as determined by your doctor.

Side effects

What side effects can occur when using Sterilid-V?

All drugs have the potential to elicit side effects even with normal use. Many side effects are route and dose-related and will likely resolve when it is adjusted or at the end of therapy.

Potential side effects while using this drug include:

  • Irritation of the eye
  • Stinging or burning sensation
  • Opportunistic fungal infections
  • Change in mental state and behavior
  • Insomnia or sleep disturbances
  • Increase intraocular pressure
  • Glaucoma
  • Papilledema
  • Cataracts
  • Vision loss
  • Impaired healing
  • Skin atrophy

Seek medical attention immediately if you experience any of these serious, potentially fatal drug reactions:

  • Adrenal insufficiency
    • Extreme fatigue
    • Weight loss
    • Decreased appetite
    • Nausea, vomiting, diarrhea
  • Stevens-Johnson syndrome (SJS)

You may experience some, none, or other side effects not mentioned above. If you have any concerns about a side effect or it becomes bothersome, consult your doctor or pharmacist.


What drugs may interact with Sterilid-V?

This drug may interact with other medications. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and inform your doctor and pharmacist.

Known drugs and their interactions with the active ingredients of Sterilid-V include:

  • CYP3A4 inhibitors
    • Increased plasma levels of Sterilid-V
  • Oral contraceptives
    • Increased plasma levels of Sterilid-V
  • Rifampicin, rifabutin
    • Decreased effect of Sterilid-V
  • Carbamazepine, phenobarbitone, phenytoin, primidone
    • Decreased effect of Sterilid-V
  • Aminoglutethimide
    • Decreased effect of Sterilid-V
  • Ephedrine
    • Decreased effect of Sterilid-V
  • Hypoglycemic agents
    • May antagonize the effects of this drug
  • Antihypertensives
    • May antagonize the effects of this drug
  • Neuromuscular blockers
    • May antagonize the effects of this drug
  • Diuretics
    • May antagonize the effects of this drug
  • Theophylline
    • Increased risk of hypokalemia
  • Cardiac glycosides
    • Increased risk of hypokalemia
  • Somatotropin
    • Decreased growth effects of this drug
  • Fluoroquinolones
    • Increased risk of tendon rupture
  • Tretinoin
    • Increased metabolism of this drug
  • NSAIDs
    • Increased risk of GI bleeding
  • Coumarin anticoagulants
    • May enhance the efficacy of these drugs

If you experience an adverse drug interaction, do not stop taking this drug. Inform your doctor immediately to reevaluate your treatment plan. Your dose may need to be adjusted, substituted with another drug, or discontinue using the drug.

Does food or alcohol interact with Sterilid-V?

This drug should be taken with meals. Certain food should be avoided while taking corticosteroids to prevent the worsening of certain symptoms. This drug does not have any significant interaction with alcohol. Your doctor or nutritionist would be able to advise you if any dietary changes should be made while taking this medication.

Inform your doctor or pharmacist if you have any concerns regarding food-drug interactions.

What health conditions may interact with Sterilid-V?

This drug should be taken with caution if you have any of the following conditions or risk factors:

  • Exposure to chickenpox or measles
  • Optic neuritis
  • Diabetes mellitus
  • Glaucoma

Inform your doctor or pharmacist if you have any concerns regarding specific health conditions.


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Sterilid-V.

What is the dose of Sterilid-V for an adult?

Instill 2 drops into the conjunctival sac of the affected eye(s) every 4 hours. If symptoms do not improve after 48 hours, the dose may need to be adjusted or the drug should be substituted.

What is the dose of Sterilid-V for a child?

The recommended dose for children has not been established. Do not give this medication to a child unless otherwise directed by a doctor.

How is Sterilid-V available?

This drug is available in the following dosage forms and strengths:

  • Sterile suspension ophthalmic drops sulfacetamide Na 10% + prednisolone acetate 0.25%

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of this drug, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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