It is also known as Adamantiades-Behcet’s syndrome.
Behcet Disease Causes
Behcet’s disease is one of the few types of vasculitis (inflammation of the blood vessels) for which a hereditary predisposition has been identified. The presence of the HLA–B51 gene increases the likelihood of developing this condition.
It is important to note, however, that having the gene does not automatically mean you will develop Behcet’s syndrome. Many people may have the gene, but only a small percentage develop Behcet disease symptoms.
Environmental triggers and exposure may also contribute to the development of the condition. Studies show that there are a variety of potential triggers, including viruses (such as the Herpes cold sore virus) and bacterial infections (from smoking, Strep throat, and other kinds of bacteria that dwell in the gut). But researchers have yet to find the underlying cause of Behcet’s syndrome.
A person’s age, sex, and country of residence are risk factors. Men in their 20s to 30s living in the Middle East and East Asian countries (particularly Turkey, Iran, Japan and China) are more prone to the disease.
Behcet Disease Symptoms
The most common Behcet disease symptoms involve:
- Painful mouth sores/ulcers (may initially look like canker sores)
- Painful genital sores (that may leave scars)
- Joint pains (on knees, ankles, elbows, or wrists)
- Recurring eye inflammation (uveitis that can cause the pain, redness, and blurry vision)
Other areas of the body that may be infected by the behcet disease symptoms are: