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Paratram (opioid analgesic, pain reliever)

Written by Stephanie Nera, RPh, PharmD · Pharmacology


Updated Jul 02, 2021

Paratram is a branded drug that contains paracetamol and tramadol. Paracetamol is a mild to moderate pain reliever (analgesic) and fever reducer (anti-pyretic). Tramadol is a moderate to severe opioid (narcotic) analgesic. This product is only available with a physician’s prescription.

paratram

Uses

What is Paratram used for?

Many conditions that cause moderate to severe pain that is not well-managed by other pain relievers. It is useful to reduce fevers.

How should I take Paratram?

Read the directions on the packaging for complete information. Check the label and expiration date.

For oral dosage forms, swallow it whole without chewing, crushing, or dissolving it in liquid. Take it with or without meals.

How do I store Paratram?

Store this product at room temperature away from direct light and moisture. To prevent drug damage, you should not store it in the bathroom or the freezer. 

There may be different brands of this drug that may have different storage needs. So, it is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush this product down the toilet or pour them into a drain unless instructed to do so. Additionally, it is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Paratram?

Before using this drug, tell your doctor if you are/have:

  • Pregnant or breastfeeding.
  • Taking any other medicines. This includes any prescription, OTC, and herbal remedies.
  • An allergy to any of the ingredients of this product, especially tartrazine.
  • Any other illnesses, disorders, or medical conditions.

Is it safe during pregnancy or breastfeeding?

Both paracetamol and tramadol cross the placenta and are present in breast milk. Long-term use of opioids can decrease fertility in women and men. In addition, prolonged use can cause neonatal withdrawal syndrome in a newborn. It is potentially life-threatening if left untreated.

Please always consult with your doctor to weigh the potential benefits and risks before taking any medication.

Side effects

What side effects can occur from Paratram?

Like all drugs, this product may have side effects. If they occur, side effects are generally mild and resolve once treatment is finished or the dose is lowered. Some reported side effects include:

  • Feeling of sickness
  • Skin reddening
  • Allergic reactions
  • Shortness of breath
  • Swollen facial features
  • Liver damage

However, not everyone experiences these side effects. In addition, some people may experience other side effects. So, if you have any concerns about a side effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Paratram?

This medication may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. 

To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. 

Drugs with known interactions:

  • Buprenorphine
  • Bupropion
  • Carbamazepine
  • Cimetidine
  • Codeine
  • If you experience an adverse drug interaction, inform your doctor immediately to reevaluate your treatment plan. Approaches include dose adjustment, drug substitution, or ending therapy.

    Does food or alcohol interact with Paratram?

    This drug may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Do not consume alcohol while taking this drug. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

    What health conditions may interact with Paratram?

    This drug may interact with underlying conditions. This interaction may worsen your health condition or alter the way the drug works. Therefore, it is important to always let your doctor and pharmacist know all the health conditions you currently have.

    Dosage

    The information provided is not a substitute for any medical advice. Therefore, you should always consult with your doctor or pharmacist before using any medication.

    What is the dose for an adult?

    Take 1 to 2 tablets every 4 to 6 hours or as needed for pain relief. The maximum dose is 8 tablets per day.

    What is the dose for a child?

    There is no established pediatric dose for children under 16 years old. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

    How is Paratram available?

    Paratram is available in the following dosage forms and strengths:

    • Film-coated tablet containing tramadol HCl 37.5 mg + paracetamol 325 mg

    What should I do in case of an emergency or overdose?

    In case of an emergency or an overdose, call your local emergency services or go to the nearest emergency room.

    What should I do if I miss a dose?

    If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

    Disclaimer

    Hello Health Group does not provide medical advice, diagnosis or treatment.

    Written by

    Stephanie Nera, RPh, PharmD

    Pharmacology


    Updated Jul 02, 2021

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