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Update Date 03/12/2020 . 4 mins read
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What is Fugerel® (flutamide) used for?

Fugerel® is a nonsteroidal antiandrogen, which is commonly used to prevent the actions of androgens (male hormones). It is used together with other hormones to treat prostate cancer.

Flutamide may also be used for other purposes. It is best to ask your doctor for more information.

How should I take Fugerel® (flutamide)?

Flutamide is usually taken every 8 hours. Drink plenty of liquids while you are taking flutamide. Your doctor may recommend a special diet to help prevent diarrhea.

You should not stop using flutamide suddenly. Stopping suddenly may make your condition worse.

Follow your doctor’s instructions.

How do I store Fugerel® (flutamide)?

Fugerel® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Fugerel® in the bathroom or the freezer. There may be different brands of Fugerel® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Fugerel® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Fugerel® (flutamide)?

You should not use this medicine if you are allergic to any ingredients of Fugerel®.

Flutamide is given as part of a combination of prostate cancer treatment with another medicine called a luteinizing hormone-releasing hormone, or LHRH. These medicines prevent the testicles from producing testosterone.

Flutamide can cause serious liver problems. Call your doctor at once if you have upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).

You will need frequent blood tests to check your liver function while you are taking flutamide.

Flutamide should never be taken by a woman or a child.

Although flutamide is not for use by women, this medicine can cause birth defects if a woman is exposed to it during pregnancy.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using Fugerel® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Fugerel®. Fugerel® is a pregnancy risk category D drug, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Fugerel® (flutamide)?

Common side effects may include:

  • Breast swelling or tenderness
  • Hot flashes
  • Vomiting
  • Diarrhea
  • Impotence or loss of interest in sex

Get emergency medical help if you have signs of an allergic reaction such as hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Fugerel® can cause serious liver problems. Call your doctor at once if you have:

  • Nausea
  • Upper stomach pain
  • Loss of appetite
  • Itching
  • Tired feeling
  • Flu-like symptoms
  • Dark urine
  • Clay-colored stools
  • Jaundice (yellowing of the skin or eyes)

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Fugerel® (flutamide)?

Fugerel® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Especially, if you also take a blood thinner (warfarin, coumadin, aspirin).

Does food or alcohol interact with Fugerel® (flutamide)?

Fugerel® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Fugerel® (flutamide)?

Fugerel® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

To make sure flutamide is safe for you, tell your doctor if you have:

  • Liver disease
  • A genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency
  • Hemoglobin M disease


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Fugerel® (flutamide).

What is the dose of Fugerel® (flutamide) for an adult?

The recommended dosage is 1 tablet, 3 times a day at 8-hour intervals preferably before gonadorelin analog treatment for a total daily dose of 750 mg.

What is the dose of Fugerel® (flutamide) for a child?

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using it. Please consult with your doctor or pharmacist for more information.

How is Fugerel® (flutamide) available?

Fugerel® is available in the following dosage forms and strengths:

  • Tablets, oral; Flutamide 250 mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Fugerel®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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