Acyclovir is an antiviral drug that has several brands. It is useful for treating a variety of viral infections. In addition, acyclovir only works for viral infections, not fungal or bacterial infections.
Written by Stephanie Nera, RPh, PharmD · Pharmacology
Acyclovir is an antiviral drug that has several brands. It is useful for treating a variety of viral infections. In addition, acyclovir only works for viral infections, not fungal or bacterial infections.
This drug treats several infections caused by herpes viruses, including:
Read the directions on the packaging for complete information. Check the label and expiration date.
Take the tablet by mouth. Swallow it whole without chewing, crushing, or swallowing it. Drink plenty of water while taking this drug to prevent kidney injury.
This product is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store it in the bathroom or the freezer.
There may be different brands of this drug that may have different storage needs. So, it is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.
You should not flush this product down the toilet or pour them into a drain unless instructed to do so. Additionally, it is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.
Before using this drug, tell your doctor if you are/have:
Herpes can be passed to your baby during childbirth if you have a genital lesion when your baby is born. If you have genital herpes, it is very important to prevent herpes lesions during pregnancy. Take your medicine as directed to best control your infection.
Herpes infections are contagious and you can infect other people, even while you are being treated. Avoid letting infected areas come into contact with other people. Avoid touching an infected area and then touching your eyes. Wash your hands frequently to prevent passing the infection to others.
Taking this medicine will not prevent you from passing genital herpes to your sexual partner. Avoid sexual intercourse while you have active lesions or the first symptoms of an outbreak. Genital herpes may still be contagious through “viral shedding” from your skin, even if you have no symptoms.
Unfortunately, there isn’t enough information about the safety of using this drug during pregnancy and breastfeeding. Acyclovir passes into breast milk and may affect a nursing infant. Please always consult with your doctor to weigh the potential benefits and risks before taking any medication.
This medication is pregnancy risk category B according to the US Food and Drug Administration (FDA).
FDA pregnancy risk category reference below:
Like all drugs, this product may have side effects. If they occur, side effects are generally mild and resolve once treatment is finished or the dose is lowered. Some reported side effects include:
Get emergency medical help if you have any of these signs of an allergic reaction to acyclovir such as hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
However, not everyone experiences these side effects. In addition, some people may experience other side effects. So, if you have any concerns about a side effect, please consult your doctor or pharmacist.
This medication may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects.
To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist.
If you experience an adverse drug interaction, stop taking this drug and continue taking your other medication. Inform your doctor immediately to reevaluate your treatment plan. Approaches include dose adjustment, drug substitution, or ending therapy.
This drug may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.
This drug may interact with underlying conditions. This interaction may worsen your health condition or alter the way the drug works. Therefore, it is important to always let your doctor and pharmacist know all the health conditions you currently have, especially:
The information provided is not a substitute for any medical advice. Therefore, you should always consult with your doctor or pharmacist before using any medication.
Genital herpes
Initial treatment is 200 mg orally every 4 hours while awake (5 times daily) for 10 days or 400 mg orally every 8 hours for 7-10 days.
Intermittent treatment for recurrence is 200 mg orally every 4 hours while awake (5 times daily) for 5 days; initiate at the earliest sign or symptom of recurrence.
Chronic suppression for recurrence is 400 mg orally every 12 hours for up to 12 months; alternatively, 200 mg 3-5 times daily.
Herpes Simplex Virus Encephalitis
The recommended dose is 10-15 mg/kg IV every 8 hours for 10 days; up to 14-21 days reported.
In obese patients, calculate the dose using body mass.
Mucocutaneous Herpes Simplex Virus Infection
Treatment in immunocompromised patients
IV: The recommended dose is 5 mg/kg every 8 hours for 7 days; dosing up to 14 days reported.
In obese patients, calculate the dose using body mass.
Herpes Zoster (Shingles)
Acute treatment: The recommended dose is 800 mg by mouth every 4 hours while awake (5 times daily) for 7-10 days.
Immunocompromised patients
Varicella-Zoster (Chickenpox)
>40 kg (immunocompetent): The recommended dose is 800 mg orally every 6 hours for 5 days.
Immunocompromised patients: The recommended dose is 10-15 mg/kg IV every 6 hours for 7-10 days.
In obese patients, calculate the dose using body mass.
Neonatal Herpes Simplex Virus Infection
The recommended dose is 30 mg/kg/day IV divided every 8 hours for 14-21 days; alternatively, 20 mg/kg IV every 8 hours for 14-21 days.
In obese patients, calculate the dose using body mass.
Herpes Simplex Virus Encephalitis
3 months-12 years: The recommended dose is 20 mg/kg IV every 8 hours for 10 days; up to 14-21 days reported.
>12 years: The recommended dose is 10-15 mg/kg IV every 8 hours for 14-21 days.
In obese patients, calculate the dose using body mass.
Mucocutaneous Herpes Simplex Virus Infection
Treatment in immunocompromised patients
<12 years: The recommended dose is 10 mg/kg IV every 8 hours for 7 days.
>12 years: The recommended dose is 5-10 mg/kg/day IV divided every 8 hours for 5-7 days; up to 14 days reported.
In obese patients, calculate the dose using body mass.
Herpes Zoster (Shingles)
Less than 12 years (immunocompromised): The recommended dose is 20 mg/kg IV every 8 hours for 7 days.
More than 12 years (immunocompetent): The recommended dose is 800 mg PO every 4 hours while awake (5 times daily) for 7-10 days
More than 12 years (immunocompromised): The recommended dose is 30 mg/kg/day IV divided every 8 hours for 7-10 days
In obese patients, calculate the dose using body mass.
Varicella-Zoster (Chickenpox)
≥2 years and <40 kg: The recommended dose is 20 mg/kg/dose by mouth every 6 hours for 5 days; not to exceed 800 mg/dose.
>40 kg: The recommended dose is 800 mg by mouth every 6 hours for 5 days.
In obese patients, calculate the dose using body mass.
Immunocompromised patients
Acyclovir is available in the following brands, dosage forms, and strengths:
In case of an emergency or an overdose, call your local emergency services or go to the nearest emergency room.
If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.
Disclaimer
Hello Health Group does not provide medical advice, diagnosis or treatment.
People Are Also Reading This
Comments
Share your thoughts
Be the first to let Hello Doctor know your thoughts!
Join Us or Log In to join the discussion