The drug trimetazidine (TMZ) allows for more blood flow to your heart and limits rapid changes in blood pressure. This can help lessen chest pain from blocked blood vessels and improve overall performance in someone with a heart-related disease. It also helps metabolize fatty acids, which helps your body use oxygen.
In Europe, TMZ is approved for the treatment of angina, but not in the United States.
What is trimetazidine?
TMZ is an antianginal agent acting at the myocardial cell (heart cell) level and shown to be effective in minimizing angina attacks, nitrate usage and improving functional capacity. It is now available in a once-daily formulation.
If you have severe kidney problems; tend to get tremors, restless legs syndrome, or other related movement disorders; under the age of 18; are allergic to any TMZ ingredients, have Parkinson’s disease or parkinsonian symptoms; are pregnant; plan to become pregnant; or are nursing, consult your doctor. Do not take any medication that is not prescribed by your doctor.
https://whellodoctor.com.ph/heart-health/heart-disease/angina-or-heart-attack/
Trimetazidine side effects
Each person will experience the side effects of TMZ differently. But frequent reactions (which can happen to up to one in 10 people) include:
- Dizziness
- Headache
- Stomach discomfort
- Diarrhea
- Indigestion
- Feeling generally nauseous
- Vomiting
- Rashes
- Itching
- Hives
This medicine may make you feel lightheaded, which may impair your ability to drive safely.
Unusual side effects
Up to 1 in 1,000 persons may experience unusual side effects, which include:
- Palpitations
- Additional heartbeats
- Adrop in blood pressure when getting up that results in lightheadedness
- Fainting
- Malaise (a general feeling of being sick)
- Odd movements like trembling and shaking in your hands and fingers
- Twisting movements in your body
- A shuffling walk
- Stiffness of your arms and legs
- Sleep problems (trouble sleeping or drowsiness)
- Constipation
- Severe skin rash that is red and burning
- Swelling of the cheeks, lips, mouth, tongue, or throat, which may make it difficult to breathe or swallow
- Substantial reduction in white blood cell count, which increases your risk of infection
- A decrease in blood platelets, which increases the possibility of bleeding or bruising
- Liver illness
Call your doctor immediately away if you have any of these negative effects from taking TMZ (or any other responses not listed).
Which interactions can trimetazidine have?
While there are currently no known drugs that interact with TMZ, it is vital to inform your doctor about any prescription or over-the-counter medications you currently use or have ever used before.
