Acromegaly is a hormonal disorder that occurs when there is too much production of growth hormone from the pituitary gland. The symptoms may only manifest at an early stage of adulthood, but the development of acromegaly may start during childhood.
Medically reviewed by Kristina Campos, MD · General Practitioner
Acromegaly is a hormonal disorder that occurs when there is too much production of growth hormone from the pituitary gland. The symptoms may only manifest at an early stage of adulthood, but the development of acromegaly may start during childhood.
This hormonal disorder often tends to relate to gigantism. In acromegaly, the attack of growth hormone is only limited to the bones in hands, feet, and face.
The progression of acromegaly in the body is slow. The changes may be difficult to recognize at an early phase. It commonly develops when a person reaches adulthood. If left untreated, this can lead to life-threatening health problems.
The location of the pituitary gland is at the base of the brain, behind the nose. Its function is to signal the liver to release insulin-like growth factors (IGF-1), which make the tissues and bones in the body grow. Too much growth hormone triggers the development of acromegaly.
These are the two types of tumors that trigger the pituitary gland in releasing excessive growth hormone:
The symptoms of acromegaly may vary depending on the person. These include the following:
The primary risk factor is a family or personal history of having a pituitary tumor.
Acromegaly is manageable, but it may lead to other health complications if left untreated. These include:
The signs and symptoms of acromegaly are hard to diagnose at an early stage. Aside from taking the patient’s history and physical examination, physicians order tests to confirm the diagnosis.
These include:
The suggested treatment varies depending on the location and size of the tumor, symptoms, and current health condition.
Treatment options include the following:
Transsphenoidal surgery is the procedure for removing pituitary tumors through the nose. In most cases, if the tumor size is small, the growth hormone level returns to normal after the surgery. It also helps in relieving the signs and symptoms, such as headaches and vision problems.
Some medications will reduce the size of the tumor and limits the production of growth hormone. These medications may be used before or after surgery.
Radiation therapy kills the tumor cells. This is done if surgery is not possible due to health conditions, and if medicines are not as effective.
Acromegaly is a rare condition related to the excessive production of growth hormone during adulthood. This is most commonly caused by a pituitary tumor that triggers the pituitary gland into stimulating more growth hormone. There are treatment options that can remove and manage the tumors. If these tumors are left untreated, it increases the risk of developing other life-threatening health complications.
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Disclaimer
Hello Health Group does not provide medical advice, diagnosis or treatment.
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