Written by

Update Date 14/08/2020 . 3 mins read
Share now


What is hordenine used for?

Hordenine is a phenylethylamine alkaloid found in barley (Hordeum vulgare) that is used to brew beer. It is similar in chemical structure to stimulants found in bitter orange. It can also be found in algae, cacti, and some grass species.

People take hordenine by mouth for improving athletic performance and weight loss. In some studies, the chemical has shown antibiotic properties and is used as a biomarker for determining the amount of beer a person has consumed.

How does it work?

The uses of hordenine are still being studied, however, some research shows that it might stimulate the central nervous system, increase heart rate, blood pressure, and breathing rate. These effects seem to be short-lived and require relatively high doses.

Precautions & warnings

What should I know before using hordenine?

Consult with your doctor or pharmacist if:

  • You are pregnant or breastfeeding. This is because, while you are expecting or feeding a baby, you should only take medicines on the recommendation of a doctor.
  • You are taking any other medicines. This includes any medicines you are taking which are available to buy without a prescription.
  • You have allergy with any substances of hordenine or other medications or other herbs.
  • You have any other illnesses, disorders, or medical conditions.
  • You have any other types of allergies, such as to foods, dyes, preservatives, or animals.

The regulations for an herbal supplement are less strict than the regulations for a drug. More studies are needed to determine its safety. The benefits of taking this herbal supplement must outweigh the risks before use. Consult with your doctor or pharmacist for more information.

How safe is hordenine?

The indicated use and safety of hordenine as a dietary supplement has not been established. As of April 2019, hordenine is on the USFDA’s Dietary Supplement Ingredient Advisory List, making it potentially unsafe.

Special precautions & warnings

Drug testing: Hordenine is excreted in urine and can potentially result in a false-positive for morphine, heroin, and other opioid drugs. Do not take this drug if you are scheduled to provide a urine sample for a drug test.

Pregnancy and breastfeeding: There is not enough reliable information about the safety of taking hordenine if you are pregnant or breastfeeding. Stay on the safe side and avoid use.

High blood pressure: Hordenine is similar to stimulants found in bitter orange. In theory, taking hordenine might make high blood pressure worse.

Kidney stones: Taking hordenine might increase the risk of kidney stones.

Surgery: Hordenine might interfere with surgery by increasing blood pressure and heart rate. Stop taking hordenine at least 2 weeks before surgery.

Side effects

What kind of side effects may I have from hordenine?

In theory, hordenine might have similar stimulant effects and side effects such as rapid heart rate and high blood pressure. Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about side effects, please consult your herbalist or doctor.


What interactions may I have with hordenine?

Hordenine may interact with your current medications or medical conditions. Consult with your pharmacist or doctor before using it.


The information provided is not a substitute for medical advice. ALWAYS consult your herbalist or doctor before using this medication.

What is the usual dose for hordenine?

The dose for hordenine may be different for every patient. The dose that you take depends on your age, health, and several other conditions. Herbal supplement are not always safe. Please discuss with your herbalist or doctor for your appropriate dosage.

What form does hordenine come in?

Hordenine may be available in the following dosage forms, although not yet approved by the FDA:

  • Encapsulated hordenine supplements
  • Hordenine HCl powder
  • A naturally occurring compund in certain food/herbs

Hello Health Group does not provide medical advice, diagnosis or treatment.

Was this article helpful for you ?
happy unhappy

FROM EXPERT Stephanie Nicole Nera


UsesAshitaba (Angelica keiskei) is an herb that grown and popularly used in Japan. It is part of the same family as carrots, celery, and parsley. The edible and medically important parts of the plant are the roots ...

Written by Stephanie Nicole Nera
Drugs 16/09/2020

Oral rehydration solution (ORS)

UsesOral rehydration salts are used to treat dehydration caused by diarrhea, fluid loss, burns, and other conditions that cause water and electrolyte deficiency. Oral rehydration salts do not treat the cause of ...

Written by Stephanie Nicole Nera
Oral rehydration solution (ORS)
Drugs 16/09/2020

Cystiphane Food Supplement

UsesCystiphane food supplement is used to build healthy and strong hair and nails. It protects hair roots and follicles while improving the quality and growth rate of hair and nails. This food supplement contains ...

Written by Stephanie Nicole Nera
Cystiphane Food Supplement
Drugs 16/09/2020

You might also like

Body Mass Index (BMI): How Does It Work?

Are you wondering how the body works and how this relates to understanding normal weight range? Read on to learn more.

Medically reviewed by Jobelle Ann Dela Cruz Bigalbal, M.D.
Written by Tracey Romero
Health Fitness 06/05/2020 . 4 mins read

Diamicron MR

Learn about Diamicron MR. What are the precautions, the warnings and how to use this drug? What should we know about its dose?

Written by Stephanie Nicole G. Nera
Drugs 03/05/2020 . 5 mins read


Learn about Prevacid. What are the precautions, the warnings and how to use this drug? What should we know about its dose?

Written by Stephanie Nicole G. Nera
Drugs 02/05/2020 . 6 mins read


Glycerin is used for weight loss, improving exercise performance, helping replace water lost, and reducing pressure inside the eye in glaucoma.

Written by Stephanie Nicole G. Nera
Drugs 02/05/2020 . 5 mins read

Recommended for you

dieting and exercising but not losing weight

8 Reasons Why You Are Not Losing Weight

Medically reviewed by Hello Doctor Medical Panel
Written by Mayvilyn Cabigao
Published on 28/08/2020 . 4 mins read
Acacia rigidula

Acacia rigidula

Medically reviewed by Stephanie Nicole G. Nera
Written by Stephanie Nicole G. Nera
Published on 18/08/2020 . 3 mins read
7-Keto DHEA

7-Keto DHEA

Medically reviewed by Stephanie Nicole G. Nera
Written by Stephanie Nicole G. Nera
Published on 18/08/2020 . 2 mins read
Hydroxycitric Acid

Hydroxycitric Acid

Written by Stephanie Nicole G. Nera
Published on 30/07/2020 . 3 mins read