Dimenhydrinate

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Update Date 14/08/2020 . 6 mins read
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Uses

What is Dimenhydrinate used for?

Dimenhydrinate is an antihistamine used to prevent and treat nausea, vomiting, and dizziness caused by motion sickness. It is also used to treat Meniere’s disease and other inner ear problems.

Do not use this medication in children younger than two years unless directed by the doctor.

How should I take Dimenhydrinate?

Take this medication by mouth with or without food. Measure liquid forms of this medication using a special measuring cup or spoon. Do not use a household spoon because you may not get the correct dose. The chewable tablets should be chewed thoroughly before being swallowed.

The dosage is based on your age, medical condition, and response to treatment. Do not increase your dose or take this medication more often than directed.

To prevent motion sickness, take the first dose 30 to 60 minutes before starting activity such as travel.

Tell your doctor if your condition does not improve or if it worsens.

How do I store Dimenhydrinate?

Dimenhydrinate is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Dimenhydrinate in the bathroom or the freezer. There may be different brands of Dimenhydrinate that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Dimenhydrinate down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Dimenhydrinate?

Before taking dimenhydrinate, tell your doctor or pharmacist if you are allergic to it; or to diphenhydramine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: breathing problems (such as asthma, emphysema), high pressure in the eye (glaucoma), heart problems, high blood pressure, liver disease, seizures, stomach/intestine problems (such as ulcers, blockage), overactive thyroid (hyperthyroidism), difficulty urinating (for example, due to enlarged prostate).

This drug may make you drowsy or blur your vision. Alcohol or marijuana can make you more drowsy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana.

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Liquid products or chewable tablets may contain sugar and/or aspartame. Caution is advised if you have diabetes, phenylketonuria (PKU), or any other condition that requires you to limit/avoid these substances in your diet. Ask your doctor or pharmacist about using this product safely.

Children may be more sensitive to the side effects of this drug. This drug can often cause excitement in young children instead of drowsiness.

Older adults may be more sensitive to the side effects of this drug, especially drowsiness, confusion, constipation, or trouble urinating. Drowsiness and confusion can increase the risk of falling.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

This drug passes into breast milk and may have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

Is it safe during pregnancy or breast-feeding?

There are no adequate studies in women for determining risk when using this Dimenhydrinate during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Dimenhydrinate. Dimenhydrinate is pregnancy risk category B according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk,
  • B=No risk in some studies,
  • C=There may be some risk,
  • D=Positive evidence of risk,
  • X=Contraindicated,
  • N=Unknown

Side effects

What side effects can occur from Dimenhydrinate?

Drowsiness, constipation, blurred vision, or dry mouth/nose/throat may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

To relieve dry mouth, suck on hard candy or ice chips, chew gum, drink water, or use a saliva substitute.

If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including mental/mood changes (such as restlessness, confusion), fast/irregular heartbeat, shaking (tremor), difficulty urinating.

Get medical help right away if you have any very serious side effects, including seizures.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side effect, please consult your doctor or pharmacist.

Interactions

What drugs may interact with Dimenhydrinate?

Some products that may interact with this drug include: antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray).

Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana, drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or other antihistamines (such as cetirizine, diphenhydramine).

Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

This medication may interfere with certain laboratory tests (including allergy skin test), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

Dimenhydrinate may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Dimenhydrinate?

Dimenhydrinate may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Dimenhydrinate?

Dimenhydrinate may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using dimenhydrinate.

What is the dose of dimenhydrinate for an adult?

For nausea and vertigo caused by Meniere’s disease & treatment of motion sickness:

Oral

Take 50-100 mg every 6-8 hours.

To prevent motion sickness, take one dose 30-60 minutes prior to activity or traveling.

IV/IM

Administer 50-100 mg every 4 hours. Maximum dose of 100 mg every 4 hours.

For IV solution reconstitution:

Dilute a 50 mg vial with 10 mL of 0.9% NaCl solution.

What is the dose of Dimenhydrinate for a child?

For nausea and vertigo caused by Meniere’s disease & treatment of motion sickness:

Oral

Age 2-6 years: 12.5-25 mg every 6-8 hours. Maximum dose of 75 mg per day.

Age 6 to <12 years: 50 mg every 6-8 hours. Maximum dose of 150 mg per day.

Age 12 and above: the same as the adult dose.

To prevent motion sickness, give one dose 30-60 minutes prior to activity or traveling.

IM

Administer 1.25 mg/kg or 37.5 mg/m2 4 times a day. Maximum dose of 300 mg per day.

How is Dimenhydrinate available?

Dimenhydrinate is available in the following brands, dosage forms, and formulations:

  • Dimezine tablets: dimenhydrinate 40 mg + cinnarizine 20 mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of dimenhydrinate, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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