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Dream Herb

Written by Stephanie Nera, RPh, PharmD · Pharmacology

Updated Sep 08, 2020


Dream Herb (Calea zacatechichi) is an herb that in the same family as daisies and sunflowers. It is native to Central America. The leaves are medium to deep green in color with occasional small, yellow flowers. The taste of the leaves is extremely bitter and may be difficult to tolerate.

This plant was given the name “Dream Herb” because of its hallucinogenic properties. In Native American and Mexican tribal cultures, it was used as a tea or smoked like tobacco. Because of its hallucinogenic properties, many states and countries have banned its cultivation and use.

Dream Herb is used as a treatment for the following:

  • Diarrhea
  • Diabetes mellitus
  • Asthma
  • Fever
  • Inflammation
  • Skin rashes
  • Upset stomach
  • Headache
  • Improve memory and mental acuity
  • Insomnia
  • Cancer
  • How does it work?

    Active compounds found in Dream Herb include flavonoids and sesquiterpenes. These compounds have cytotoxic effects, which have a benefit in cancer treatment.

    Extracts of Dream Herb may also inhibit cytochrome P450 enzyme expression, which may interact with the metabolism of certain hormones and drugs.

    Many of the health effects of Dream Herb are not yet attributed to specific compounds. More research needs to be done to elucidate the active constituents of Dream Herb and their mechanisms of action to better understand how this herb works.

    Precautions & Warnings

    Herbal supplements are generally safe to take in moderate amounts as directed by a health professional. However, because most herb and food supplements are not approved by the FDA for treating and preventing specific diseases, recommended daily values are not always established.

    Despite being advertised as “all-natural” or “safe”, natural or food supplements must be treated as conventional medication. Certain herbal preparations can interact with other medications you are taking, increasing the risk of adverse drug reactions and toxicity.

    Before using this medication, inform your doctor if:

    • You have ever had an allergic reaction to Dream Herb or other supplements.
    • You have a history of allergy to other medications, food, or other substances.
    • You are taking other medications.
    • You have underlying health conditions.

    Is it safe during pregnancy or breastfeeding?

    There is insufficient data regarding the use and safety of this supplement during pregnancy. This supplement should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus, as determined by your doctor.

    It is not known if the active compounds are excreted into breast milk. This supplement should be used while breastfeeding only if the potential benefit justifies the potential risk to the child, as determined by your doctor.

    Side Effects

    What side effects can occur from Dream Herb?

    All supplements have the potential to elicit side effects even with normal use. Many side effects are dose-related and will resolve when it is adjusted or at the end of therapy.

    Potential side effects while using this supplement include:

    • Gastrointestinal discomfort
    • Throat or lung irritation
    • Coughing
    • Lucid dreams
    • Nightmares

    You may experience some, none, or other side effects not mentioned above. If you have any concerns about a side effect or it becomes bothersome, consult your doctor or pharmacist.


    To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and inform your doctor and pharmacist.

    The liquid extract preparation of this medication may contain alcohol. Avoid taking the following together with this preparation:

    • Antihistamines
    • Sedatives
    • CNS depressants

    If you experience an adverse drug interaction, stop taking this drug and continue taking your other medication. Inform your doctor immediately to reevaluate your treatment plan. Your dose may need to be adjusted, substituted with another drug, or discontinue using the drug.

    Does food or alcohol interact with Dream Herb?

    This medication may be taken with or without food. If you experience any gastrointestinal discomfort, taking this medication with meals may prevent this symptom. It is important to drink enough water while taking this medication.

    The liquid extract preparation of this medication may contain alcohol thus alcohol consumption should be limited to prevent intoxication, especially in children or adults who need to drive or operate machinery.

    Inform your doctor or pharmacist if you have any concerns regarding food-drug interactions.

    What health conditions may interact with Dream Herb?

    This supplement should be taken with caution if you have any of the following conditions or risk factors:

    • Allergy to any of the ingredients
    • Renal impairment

    Inform your doctor or pharmacist if you have any concerns regarding specific health conditions.


    The information provided is not a substitute for professional medical advice. You should ALWAYS consult your doctor or pharmacist before using Dream Herb.

    What is the dose of Dream Herb for an adult?

    The recommended dosage of this drug has not been established for treating any specific disease or condition. Consult a doctor for the appropriate indication and dosage.

    What is the dose of Dream Herb for a child?

    This supplement is not recommended for use in children and the recommended dose has not been established. Consult with a doctor or pharmacist for alternatives and more information.

    How is Dream Herb available?

    This supplement is available in the following dosage forms:

    • Liquid extract
    • Tea
    • Dry herb
    • Capsule

    What should I do in case of an emergency or overdose?

    In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

    What should I do if I miss a dose?

    If you miss a dose of this supplement, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.


    Hello Health Group does not provide medical advice, diagnosis or treatment.

    Written by

    Stephanie Nera, RPh, PharmD


    Updated Sep 08, 2020

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