How to Prevent Parkinson’s Disease

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Update Date 03/12/2020 . 4 mins read
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While scientists can point out several risk factors that contribute to Parkinson’s Disease (PD) development, its exact cause is still not clear. The mystery surrounding the cause makes it even more challenging to stop PD before it happens. In this article, we’ll discuss the best practices that potentially prevent Parkinson’s disease.

Brain and Spine Disorders: Everything You Need to Know

The features of Parkinson’s Disease

Before we go to the different practices that potentially prevent Parkinson’s Disease, let’s first briefly discuss the disease’s pathological features. Pathological features are characteristics or changes common among patients of a specific illness.

In PD, scientists had discovered that patients have low levels of dopamine, a neurotransmitter that sends messages between nerve cells. Additionally, they have high levels of a protein called alpha-Synuclein or alpha-Syn.

Researchers have already counted these changes as a part of the possible causes of PD, but they are still trying to understand why they happen. As such, the exact cause of PD remains a mystery.

But, the good news is people can take simple steps to improve their dopamine and alpha-Syn levels. Research shows that the practices below can potentially prevent Parkinson’s Disease.

how to prevent Parkinson's disease

3 Practices to prevent Parkinson’s disease

Exercise regularly

A practical way to reduce the risk of Parkinson’s Disease is to be physically active.

Exercise is one of the recommended treatment practices for PD. Doctors emphasize that patients should build their strength, balance, and endurance as they will need them later on to combat the effects of late-stage complications.

Now, there’s a good reason to believe that exercise can also help prevent Parkinson’s Disease. Various studies point out that people with the highest levels of moderate to vigorous physical activities have the lowest PD risk. One particular study with over 213,000 participants even noted that physical activity reduces the risk by up to 40%.

How exercise helps:

While it’s not yet clear how exactly exercise helps prevent Parkinson’s Disease, researchers believe it’s because exercise offers numerous brain-protecting benefits, including:

  • Activating the neurons responsible for motor control
  • Increasing blood flow to different parts of the brain
  • Promoting neural plasticity, which improves balance and motor control; plasticity is the brain’s capacity to make connections between brain cells
  • Reducing dopamine loss
  • Reducing the accumulation of alpha-Syn protein

What you can do:

Consider increasing your levels of moderate to vigorous physical activities. Examples of moderate to vigorous exercises are:

  • Brisk walking
  • Bicycling
  • Recreational badminton
  • Tennis
  • Hiking
  • Jogging
  • Basketball game

Just a little reminder: Don’t forget to talk to your doctor about any plans to change your exercise routine.

Drink coffee

The next simple step to take to prevent Parkinson’s Disease is to drink coffee. One study involving 8,000 Japanese-American men reveals that increased caffeine intake is related to decreased Parkinson’s Disease incidence.

What’s even more promising is that the study results were independent of other factors such as smoking. This means that increased caffeine intake reduces PD incidence in participants who were never, former, and current smokers.

The researchers also emphasized that there was no significant relationship between PD risk and the other nutrients in coffee. Likewise, the results were unaffected by milk and sugar.

Overall, the study concluded that people who don’t drink coffee are 5 times more likely to develop PD than the participants who take 28oz (828 ml or 3.5 cups) of coffee daily.

How coffee helps:

We need more studies to confirm how coffee reduces PD risk, but comments on the study mentioned that years of exposure to caffeine might counteract the age-related loss of dopamine.

What you can do:

You can consider increasing your caffeine intake. According to the USFDA, 400 mg (4 to 5 cups) of coffee daily is generally not associated with adverse effects. However, caffeine sensitivity varies from person to person, so consult your doctor first about acceptable coffee consumption.

how to prevent Parkinson's disease

Drink green tea

Finally, to help prevent Parkinson’s disease, you can drink green tea. There are still no human clinical trials that analyze the effects of green tea on Parkinson’s Disease, but scientists have identified specific components in it that may reduce the risk of PD.

How green tea helps:

Reports indicate that the polyphenols in green tea are capable of protecting the neurons that produce dopamine. Moreover, scientists highlight that the neuroprotective property “increases with the amount consumed.”

An antioxidant in green tea called Epigallocatechin Gallate or EGCG also seems to “inhibit” the protein alpha-Syn.

What you can do:

Since there are still no human clinical trials about green tea and its effects on PD risk, the safest thing to do is talk to your doctor about it.

Experts say that a few cups (up to 5) of green tea daily may offer many health benefits, but don’t overdo it. Moreover, be sure to choose high-quality green tea brands and not beverages that have a lot of added sugars.

Key Takeaways

There’s still no identified means to prevent Parkinson’s Disease. But studies show that regular exercise and the intake of caffeine and green tea might help reduce the risk of Parkinson’s disease.

Learn more about Parkinson’s Disease here

Hello Health Group does not provide medical advice, diagnosis or treatment.

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Parkinson Disease is a certain type of movement disorder that leads to shaking, stiffness, difficulty maintaining balance, hand-eye coordination, or any form of coordination relating to the patient’s body. Parkinson's Disease occurs when the brain’s nerve cells don’t produce enough dopamine, a neurotransmitter and hormone that plays several roles in the brain and body, including sending messages between nerve cells. Let's learn more about Parkinson's Disease cure research here.  Symptoms of Parkinson’s Disease In general, symptoms develop gradually, often concentrating on one side of the body, eventually progressing to a point where both sides of the body are affected. Symptoms include: Trembling of body parts, notably the jaw, face, hands, arms, and legs Slowness and clumsiness of movement Severely debilitated balance and coordination Stiffness of certain body parts, such as the trunk, arms, and legs In later stages, and as symptoms worsen, people with the disease begin to struggle with talking, walking, and fulfilling simple tasks. Symptoms also include but are not limited to Trouble with sleeping Depression Difficulty controlling the mouth with regards to chewing, swallowing, or speaking Parkinson's Disease Cure Research In recent years, there has been no specific test developed for Parkinson’s Disease, thus creating difficulty in diagnosing patients. Medical practitioners relied on neurological examinations and medical history to determine if a patient is afflicted with the disorder.  Although there is no cure for Parkinson’s disease at this time, medicines, surgical treatment, and different forms of therapy have been developed to help patients in alleviating the symptoms they experience. Medication for Parkinson Medications designed for Parkinson’s Disease generally comprise 3 categories: 1. Medicines that aim to increase the brain’s dopamine levels The most prevalent drugs for Parkinson’s Disease are dopamine precursors. This includes substances including levodopa, which cross the barrier between the blood and the brain, which in turn are transformed into the much needed dopamine for the patient. Several other drugs aim to copy the effects of dopamine to purposely act as its replacement. 2. Drugs affecting neurotransmitters in the patient’s body for the purpose of mitigating the effects of Parkinson’s Disease Prime examples of such are anticholinergic drugs that stagnate the generation of acetylcholine, a type of neurotransmitter. Drugs of this category can significantly help in reducing the occurrence of tremors for patients. 3. Drugs that aim to affect the non-motor symptoms of Parkinson’s disease This refers to patients who express symptoms of depression, for example, and require medicines that classify as antidepressants. Symptoms may drastically ameliorate within the first assessment after administering medication. But effects and symptoms may resurface over time, as the development of Parkinson escalates, with symptoms worsening and medicines possessing less effects as resistance develops. This puts pressure on Parkinson’s Disease cure research to find a permanent solution to this disease. At any rate, medications designed to stem the effects and symptoms of Parkinson’s disease consist of: Levodopa/Carbidopa Regarded as the most prevalent and successful medication for Parkinson Disease, which is sometimes referred to as L-Dopa. The drug works in such a way that the body’s cells use the drug to generate dopamine and replenish the brain’s lacking supply of cells. It is worth noting that patients are not able to utilize dopamine medications due to the fact that dopamine does not readily move through the barrier between the patient’s blood and brain. In most cases, patients are prescribed levodopa in combination with another medication known as carbidopa. Levodopa and/or carbidopa are known to have a high success rate at reducing or eliminating the symptoms associated with motor symptoms of Parkinson Disease during its early stages. Levodopa usually assists patients by mitigating the effects of Parkinson pertaining to movement.  Dopamine agonists These drugs aim to replace or mimic the role of  the substance dopamine in the patient’s  brain and can be given alone or in combination with levodopa. They are regarded as a lackluster treatment in comparison to levodopa  in terms of treating Parkinson symptoms, but are also known to work on patients for a longer duration. Most of the potential side effects of dopamine agonists are similar to what is experienced by patients who use levodopa. Such symptoms include: Onset of sleep that is sudden or spontaneous in nature Symptoms relating to drowsiness Occurrence of hallucination, and confusion, vomiting Onset of nightmares In rare cases, said agents may create an uncontrollable desire for patients to do specific actions.  The same are also responsible for creating tense feelings in patients that may relate  to hypersexuality, gambling, or compulsive shopping. All of which are examples of impulsive behavior. Dopamine agonist drugs consist of  pramipexole, apomorphine, rotigotine, and ropinirole. MAO-B inhibitors Drugs identified as such aim to block or inhibit monoamine oxidase B, a specific type of enzyme otherwise known as MAO-B, which serves to break down existing dopamine in the patient’s brain. MAO-B inhibitors are also known to be responsible for the accumulation of dopamine in nerve cells, thus mitigating the severity of PD’s symptoms. Examples of drugs that are regarded as MAO-B inhibitors are rasagiline and selegiline. Amantadine This drug is antiviral in nature and serves to help reduce Parkinson Disease symptoms and levodopa-induced dyskinesia. It may be prescribed to the patient without any accompanied drugs in the first stages of Parkinson. The same may also be  used in combination with an anticholinergic drug, and even levodopa. Amantadine’s side effects mainly consist of edema, mottled skin, insomnia, the occurrence of hallucinations, and patient’s agitation. Surgery Surgical treatment is reserved for patients who do not respond well to medications, and is identified as DBS, or Deep Brain Stimulation. It is a surgical procedure that implants electrodes into the patient’s brain, that is then connected to a device attached to the patient’s chest, creating a stimulation in the brain that is painless for the patient and which rebukes many of the problems Parkinson brings in relation to the movement of the patient. Therapy Therapy includes but is not limited to occupational, physical and speech therapy. These are known to assist patients with tremors, rigidity, gait disorders, voice disorders. These also give other benefits to patients depending on their current situation. Therapy is a viable option as it may be customized and designed to suit the patient’s needs. Interestingly enough, research on Parkinson Disease has gained traction and recent advances have helped in improving symptomatic therapy for motor and non-motor symptoms of patients, though research on a definitive cure is still ongoing and some efforts are being turned into collectives. For example, The National Institute of Neurological Disorders and Stroke, otherwise known as NINDS, has formed collectives to seek fundamental knowledge of the brain and use available information to conduct research on ideas that may direct them towards a cure, or at least to create an effort to help reduce the severity of symptoms on patients. In 2014, the same institution organized the Parkinson’s Disease 2014: Advancing Research, Improving Lives Conference, which gave birth to a collaboration of researchers, clinicians, patients and benefactors to create a total of 31 recommendations for Parkinson Disease research. Another example of a research breakthrough is the discovery of a Genetic “switch,” and the possibility of it preventing the symptoms of Parkinson Disease altogether. The research was conducted by the Medical Research Council at the University of Leicester in 2017. The study focused on the gene ATF4 and its key role in Parkinson Disease.  Key Takeaways What steps have been made in Parkinson's Disease cure research? Researchers all over the world are still working on developing a cure. However, a multitude of breakthroughs has been developed. These mitigate and, in some cases, prevent the progression of Parkinson Disease symptoms altogether. And that is no small feat. While a number of Old Adults are at risk, any of the aforementioned treatment methods may prove effective in mitigating the development of their symptoms. Learn more about Parkinson's Disease here. 

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