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What Is Niacinamide? What Can It Do for Your Skin?

What Is Niacinamide? What Can It Do for Your Skin?

What is niacinamide? It is a water-soluble, active form of niacin or vitamin B3 that is usually present in different food, such as:

  • Lean meat
  • Fish
  • Yeast 
  • Nuts
  • Legumes
  • Eggs
  • Milk
  • Cereals
  • Green vegetables

When more niacin is consumed than the body requires, it is then converted to niacinamide. The body needs this component in small amounts for fats and other sugars in the body to properly function, as well as to maintain healthy cells. Some also use niacinamide to treat different conditions, including diabetes, osteoarthritis, vitamin B3 deficiency, and even cancer.

Niacinamide is often seen in products that treat skin conditions like:

As a result, it is often incorporated in many topical skincare products, including serums, sunscreens, and other cosmetic agents.

Some people also refer to it as nicotinamide or nicotinic acid amide.

How Can The Skin Benefit from Niacinamide?

Topical niacinamide provides benefits for the skin thanks to its anti-inflammatory, anti-itching, anti-microbial, and antioxidant properties. 

Help in Acne Treatment

One of the notable benefits of niacinamide is its capability to treat acne problems with its anti-inflammatory properties

In a controlled clinical trial of 76 participants with moderate acne, 4% nicotinamide gel showed comparable effectivity to the topical antibiotic 1% clindamycin gel in treating acne. Moreover, it also aids in the reduction of sebum production on the face that could help prevent acne buildup

Improve the Skin Barrier

Studies also show that niacinamide can enhance the skin’s barrier function. This is made possible by reducing water loss through the epidermis, thus resulting in improving skin hydration

In another study, niacinamide helped protect the skin cells from oxidative stress. 

Furthermore, people with rosacea may also benefit from this particular functionality of niacinamide. Two studies mentioned its effectiveness in reducing reactions to such irritants as with other cleansers and cosmetics. 

Niacinamide Has Anti-aging Properties

Multiple clinical studies indicate that topical niacinamide has good effects on skin by improving fine lines, wrinkles, and elasticity. Apart from that, it also helps in treating hyperpigmented spots and red blotchiness. 

According to one study, it stimulates the skin’s production of ceramides that are known as natural emollients and skin protectants. Thus, it helps in enhancing skin appearance, as well as hydration. 

Help in Hyperpigmentation and Melasma 

Researchers discovered that the use of niacinamide as a treatment for melasma brought significant results in reducing hyperpigmentation. Consistent use of the product for two weeks also revealed a decrease in erythema and papules by 50-75%.

Key Takeaways


What is niacinamide? It is a potent substance that can help you treat many skin concerns. Apart from treatment use, this skincare product can also prevent signs of aging. 
Niacinamide is generally safe when taken/ applied at the right dose, but because this is a potent substance, you may want to consider doing a patch test first on your wrist to check if your skin reacts to it.
Also note that it can produce adverse effects like sweating, increase in blood sugar, low blood pressure, and nausea. It is better to consult a specialist if you experience any of these, especially if you’re currently taking other medications which can have an interaction with it.

Learn more about Skin Care and Cleansing here

Disclaimer

Hello Health Group does not provide medical advice, diagnosis or treatment.

A review of nicotinamide: treatment of skin diseases and potential side effects – Heidi M. Rolfe, https://pubmed.ncbi.nlm.nih.gov/25399625/, Accessed January 7, 2022

How Much Do We Really Know About Our Favorite Cosmeceutical Ingredients? – Jacquelyn Levin, DO and Saira B. Momin, DO, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921764/, Accessed January 7, 2022

Niacinamide, https://www.cancer.gov/publications/dictionaries/cancer-terms/def/niacinamide, Accessed January 7, 2022

Niacinamide, https://medlineplus.gov/druginfo/natural/1534.html, Accessed January 7, 2022

Niacinamide Protects Skin Cells from Oxidative Stress Induced by Particulate Matter – Ao Xuan Zhen, Mei Jing Piao, Kyoung Ah Kang, Pincha Devage Sameera Madushan Fernando, Hee Kyoung Kang, Young Sang Koh, Joo Mi Yi, and Jin Won Hyun, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824628/, Accessed January 7, 2022

Nicotinamide, https://dermnetnz.org/topics/nicotinamide, Accessed January 7, 2022

Nicotinic acid/niacinamide and the skin – W Gehring, https://pubmed.ncbi.nlm.nih.gov/17147561/, Accessed January 7, 2022

The role of nicotinamide in acne treatment – Frances M Walocko, Ariel E Eber, Jonette E Keri, Mana A Al-Harbi, Keyvan Nouri, https://pubmed.ncbi.nlm.nih.gov/28220628/, Accessed January 7, 2022

Current Version

10/11/2022

Written by Fiel Tugade

Medically reviewed by Sue Kua, MD

Updated by: Lorraine Bunag, R.N.


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Medically reviewed by

Sue Kua, MD

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Written by Fiel Tugade · Updated Oct 11, 2022

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