On the other hand, herpes zoster has been associated with immune suppression and an increased risk of cancer. Research published in 1982 did not support the investigation of patients for occult cancer at the time of diagnosis of herpes zoster. It did not support enhanced surveillance for cancer after diagnosis either.
That is in contrast with a 2016 study. A systematic review and meta-analysis of evidence on herpes zoster and risk of occult cancer was conducted. This study supported an association between herpes zoster and occult cancer. However, the low absolute risk of cancer limits the clinical implications.
Patients being treated for cancer, also for herpes simplex virus
To examine the effects of interventions for the prevention of HSV patients being treated for cancer, research has been undertaken. The effects of treatment for the herpes simplex virus were also studied. The cancer treatment was increasingly effective but associated with a viral infection such as HSV, noted the research published in 2009.
Recurrent HSV type 1 infection in patients who are immunocompromised due to treatment for cancer may be more aggressive, painful, and slower to heal. These more extensive lesions often require much longer treatment. These may leave the patient more susceptible to developing drug‐resistant strains of HSV.
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