How long is the projected time to find the cure and vaccine for COVID-19?
The cure and vaccine for COVID-19 have been reported to be ready as early as September of this year However, experts cannot give a definite timeline. This is because it takes time, trials, and continuous financial support to develop them. So far, we have the following developments:
What are the worldwide developments in finding the cure and vaccine for COVID-19?
To end the pandemic, the population must be given immunity against the COVID-19. However, that is only possible if an effective vaccine can be developed.
A vaccine contains an agent from the disease-causing organism (pathogen). It is often prepared from the weakened or dead bacteria or virus. When a person receives the vaccine, their body will recognize the pathogen and produce antibodies against it. This allows the person to build immunity.
While a lot of people think that a vaccine will be ready by the end of 2020, others think that it may take longer. This is because vaccines need to undergo several phases of trials before they can be deemed safe for use.
According to the Global Alliance for Vaccine and Immunisation (GAVI), should a candidate vaccine make it past the pre-clinical trial, it still has to undergo the 3-phase human trial. Phase 1 tests for safety and dosage of the candidate vaccine. Phase 2 needs more tests are done to check the effectiveness and safety of the candidate vaccine. Lastly, Phase 3 assesses the effectiveness of the vaccine and determines its possible side effects.
Cure and vaccine for COVID: Candidate Vaccines
As of now, there are several vaccine candidates in Phase 3 clinical trial.
For instance, there’s CanSino Biologics Inc.’s Ad5-nCoV. According to reports, Ad5-nCoV is generally safe. People who have received this candidate vaccine effectively developed immunity in the early tests.
Then, there’s the Wuhan Institute of Biological Products’ Inactivated Vaccine. In Phase 1 of the clinical trial, 96 people from different age groups participated. The trial commenced on April 23 of this year.
Moderna’s mRNA 1273 candidate vaccine also showed great results in its Phase 1 and 2 Trial, so it’s not surprising that it’s also in its 3rd Phase now.
Finally, these other vaccine candidates also made it to Phase 3:
- AZD1222 from AstraZeneca and the University of Oxford
- Sinovac’s CoronaVac Inactivated Vaccine
- Novavax’ NVX-CoV2373
Johnson&Johnson’s JNJ-78436735 made it to Phase 3, too. However, the company announced on October 12, 2020 that they had to pause the trial because of an “unexplained illness in a study participant.” As of now, they still do not know if the unexplained illness is connected to the vaccine candidate, but there is an ongoing review and evaluation.