A 3-month study involving more than 10 million people found that Sinovac has 65% effectiveness in preventing COVID-19. It is also 87.5% effective in preventing hospitalization, 90.3% effective in preventing ICU admission, and 86.3% effective in preventing COVID-related death³.
Vaxzevria (AstraZeneca) and Comirnaty (Pfizer)
One report noted that 20+ weeks after the second dose, AstraZeneca and Comirnaty are 77% and 92.7% effective against hospitalization respectively. Against death, Vaxzevria is 78.7% effective while Pfizer is 90.4% effective⁴.
One report stated that 2 doses of Moderna strongly protect against COVID-19. The report also mentioned that there was no data regarding hospitalization because “there were no hospitalizations with non-delta variants identified among vaccinated people.” Experts also noted that Moderna has 97.5% effectiveness against Delta-related hospitalizations⁵.
According to experts, single-shot Janssen has the lowest effectiveness rate compared to mRNA giants, Pfizer and Moderna. While its VE is stable, (at least 70%), one study noted that 5 months after the inoculation, the effectiveness drops to 59.4%⁶.
Most vaccines show waning or diminishing effectiveness on new variants, particularly for Delta and Omicron. When it comes to protection against mutations, what’s the best vaccine for COVID-19?
A news report stated that three doses of Sinovac fail to protect against Omicron. That’s why people who received two doses must seek a different brand⁷.
The US Center for Disease Control also released a report saying that the VE of mRNA vaccines is higher in people who got their vaccine less than 180 days ago compared to those who had their second dose more than 180 days ago.
They also said that a third dose was highly effective in preventing emergency care, hospital admissions, and death during the Delta and Omicron pre-dominant periods.
The implication is that people should get their booster shot as soon as they are already eligible for it.
We cannot talk about the best vaccine for COVID-19 without discussing the side effects.
Before 2021 ended, the Center for Disease Control released a statement saying they prefer Pfizer and Moderna over J&J. This happened after they learned that the cases of blood clotting disorder following J&J vaccination were higher than they initially believed.
That’s not to say that Pfizer and Moderna don’t have rare, serious side effects. Experts also associate these mRNA vaccines with myocarditis or inflammation of the heart muscle.
Studies also associate Oxford AstraZeneca with a rare blood clotting disorder.