Uses
What is Moriamin S-2 used for?
Moriamin S-2 is a preparation containing essential and non-essential amino acids, glycine, and sorbitol. Amino acids are considered the building blocks of proteins, owing to their nitrogen content. They are necessary for the synthesis of important substances like neurotransmitters, hormones, and muscle fibers.
Essential amino acids cannot be synthesized by the human body and must be obtained through food such as meat and other sources of protein. Non-essential amino acids are normally obtained through a series of intracellular metabolic processes.
Moriamin S-2 is mainly indicated to treat the following conditions:
- Hypoproteinemia
- Malnutrition
- Pre- and post-operation
How should I take Moriamin S-2?
Moriamin S-2 is available as a parenteral solution for infusion. It is injected through the intravenous (IV) route and should not be taken as an oral solution. The dose must be administered slowly via IV infusion to minimize injection site irritation and adverse effects. It should be administered by a licensed health professional.
How do I store Moriamin S-2?
This drug should be stored at room temperature (<30°C) and be protected from light and moisture. Do not allow this product to freeze. Crystallization may occur at low temperatures. Before use, warm it to 50-60°C and administer it when the temperature cools to normal body temperature (~37°C).
Always check the label before using this product. Do not use if the printed expiration date has passed, the product seal has been broken, or the product has changed in color, odor, or consistency. For safety, keep out of the reach of children and pets.
Do not dispose of this product by pouring it down the drain, toilet, or into the environment. Ask your pharmacist regarding the proper way and location of disposal.
Precautions & Warnings
What should I know before using Moriamin S-2?
Each amino acid preparation is uniquely blended and designed to treat metabolic disorders, supplement nutritional requirements, or correct deficiencies. Moriamin S-2 may not be a suitable substitute for other amino acid solutions to treat a specific condition.
Moriamin S-2 contains sodium and chloride in addition to amino acids so careful monitoring of electrolyte balance is necessary when given with an electrolyte solution or in large doses.
Before using this medication, inform your doctor if:
- You have ever had an adverse reaction to Moriamin S-2 or other amino acid preparations
- You have a history of allergy to other medications, food, or other substances
- You are taking other medications, especially other sources of electrolytes
- You have underlying health conditions, such as congestive heart failure
Is it safe during pregnancy or breastfeeding?
During pregnancy, protein and amino acid requirements are increased to support both maternal health and fetal growth. Generally, amino acid administration is safe, even necessary in certain cases. However, the types and doses of amino acids should be individualized for each patient.
This preparation should be used during pregnancy only when necessary.
This drug may be excreted in breast milk. This drug should be used while breastfeeding only when necessary.
Side Effects
What side effects can occur when using Moriamin S-2?
All drugs have the potential to elicit side effects even with normal use. Many side effects are dose-related and will resolve when it is adjusted or at the end of therapy.
Potential adverse effects while using this drug include:
- Hypersensitivity reactions (e.g. rash)
- Nausea, vomiting
- Chest discomfort
- Palpitations
- Acidosis
- Chills
- Fever
- Headache
- Vascular pain
You may experience some, none, or other side effects not mentioned above. If you have any concerns about a side effect or it becomes bothersome, consult your doctor or pharmacist.
Interactions
What drugs may interact with Moriamin S-2?
This drug may interact with other medications. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and inform your doctor and pharmacist.
Known drugs and their interactions with Moriamin S-2 include:
- Electrolyte solutions
- Possible risk of hypernatremia and hyperchloremia
If you experience an adverse drug interaction, stop taking this drug and continue taking your other medication. Inform your doctor immediately to reevaluate your treatment plan. Your dose may need to be adjusted, substituted with another drug, or discontinue using the drug.
Does food or alcohol interact with Moriamin S-2?
There are no significant food or alcohol interactions with this drug.
Inform your doctor or pharmacist if you have any concerns regarding food-drug interactions.
What health conditions may interact with Moriamin S-2?
This drug should be taken with caution if you have any of the following conditions or risk factors:
- Abnormal amino acid metabolism
- Metabolic acidosis
- Electrolyte imbalance
- Congestive heart failure
- Diabetes mellitus
- Renal disorders
- Elderly patients (>60 years)
Inform your doctor or pharmacist if you have any concerns regarding specific health conditions.
Dosage
The information provided is not a substitute for any medical advice. You should ALWAYS consult your doctor or pharmacist before using Moriamin S-2.
What is the dose of Moriamin S-2 for an adult?
Via IV infusion or IV drip
- Administer 20 to 500 mL slowly through a suitable vein.
- Rate of infusion: 200 mL in 80 to 100 minutes (approximately 30 to 40 drops per minute). Use a slower rate for children, elderly, and patients in poor condition.
Note: All doses should be calculated and adjusted based on the patient’s age, symptoms, and body weight.
What is the dose of Moriamin S-2 for a child?
The recommended dose of Moriamin S-2 in children has not been established. Consult a doctor or pharmacist for alternatives and more information.
How is Moriamin S-2 available?
This drug is available in the following dosage forms and strengths:
- Parenteral solution for injection in 20 mL ampules, 200 mL vials, and 500 mL vials
- Every 20 mL of solution contains: 0.11 g L-isoleucine, 0.246 g L-leucine, 0.446 g of L-lysine HCl, 0.142 g L-methionine, 0.174 g L-phenylalanine, 0.108 g L-threonine, 0.036 g L-tryptophan, 0.122 g L-valine, 0.16 g L-arginine HCl, 0.08g L-histidine HCl, 0.2 g glycine, 1 g D-sorbitol, total nitrogen: 13.1 mg/mL, sodium (Na) 18 mEq/L, chloride (Cl) 182 mEq/L
What should I do in case of an emergency or overdose?
In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.
What should I do if I miss a dose?
If you miss a dose of this drug, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.
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