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Update Date 08/05/2020 . 4 mins read
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What is methycobal (methylcobalamin) used for?

Methycobal is commonly used for:

  • Treating and preventing vitamin B12 deficiency.
  • Treating pernicious anemia; treating memory loss; Alzheimer’s disease; boosting mood, energy, concentration and the immune system; and slowing aging.
  • Treating heart disease, lowering high homocysteine levels (which may contribute to heart disease), male infertility, diabetes, sleep disorders, depression, mental disorders, weak bones (osteoporosis), swollen tendons, AIDS, inflammatory bowel disease, asthma, allergies, a skin disease called vitiligo, preventing cervical and other cancers, and skin infections.
  • Treating amyotrophic lateral sclerosis(Lou Gehrig’s disease), multiple sclerosis, preventing the eye disease age-related macular degeneration (AMD), Lyme disease and gum disease.
  • Treating ringing in the ears, bleeding, liver and kidney disease, and for protection against the poisons and allergens in tobacco smoke.

How should I take methycobal (methylcobalamin)?

For orally taken form, you should:

  • Take methycobal by mouth as directed by your doctor concerning: dose, schedule.
  • Read the label carefully before using methycobal.
  • Consult your doctor for any information on the label that you do not clearly understand.

How do I store methycobal (methylcobalamin)?

Methycobal is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store methycobal in the bathroom or the freezer. There may be different brands of methycobal that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush methycobal down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using methycobal (methylcobalamin)?

Before using methycobal, tell your doctor if you have:

  • Allergic reaction: to methycobal, excipients using for dosage form containing methycobal. The information is detailed in the leaflet.
  • Allergic reaction to any other medicines, foods, dyes, preservatives, or animals.
  • Pediatric.
  • Geriatric.
  • Used any other health conditions, drugs that have a risk of interaction with methycobal.

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using methycobal during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking methycobal.

Side effects

What side effects can occur from methycobal (methylcobalamin)?

As taking others medicines, taking methycobal can cause some side effects. Most of them are rarely occurring and do not need any supplementary treatment. However, it is always important for you to consult your doctor if you have any problem after taking this medicine.

Some of the side effects are listed below:

  • Headache;
  • Itching;
  • Swelling;
  • Nervousness and anxiousness;
  • Involuntary or uncontrollable movements;
  • Low levels of potassium in the blood;
  • Congestive heart failure;
  • Clots in the arms and legs;
  • Life-threatening allergic reaction called anaphylaxis, in which you may have trouble breathing, your tongue swells and/or throat closes up, and your skin breaks out into hives;
  • Fluid building up in the lungs.

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side effect, please consult your doctor or pharmacist.


What drugs may interact with methycobal (methylcobalamin)?

Methycobal may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval, such as:

  • Leukeran (chlorambucil);
  • Prilosec (omeprazole);
  • Colcrys and Mitigate (colchicine);
  • The herbal supplement goldenseal.

Does food or alcohol interact with methycobal?

Methycobal may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with methycobal (methylcobalamin)?

Methycobal may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using methycobal (methylcobalamin).

What is the dose of methycobal (methylcobalamin) for an adult?

Consult your doctor for information about the dose of methycobal (methylcobalamin) hydrochloride.

For Peripheral Neuropathies 

Oral: 3 tablets daily in 3 divided doses. 

Parenteral: 1 ampule IM or IV 3 times per week. 

Megaloblastic Anemia 

Parenteral: 1 ampule IM or IV 3 times per week. 

  • After 2 months, reduced to single administration of 1 ampule at 1-3 month interval as maintenance.

What is the dose of methycobal (methylcobalamin) for a child?

Consult your doctor for information about the dose of methycobal (methylcobalamin) hydrochloride.

The dosage has not been established in pediatric patients. It may be unsafe for your child. It is always important to fully understand the safety of the drug before using. Please consult with your doctor or pharmacist for more information.

How is methycobal (methylcobalamin) available?

Methycobal (methylcobalamin) is available in the following dosage forms and strengths:

Ampule for injection (IM/IV): 500 mcg/mL

Tablet, oral: 500 mcg 

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services (115) or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of methylcobal (methylcobalamin), take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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