Ketotifen

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Published on 14/08/2020 . 4 mins read
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Uses

What is ketotifen used for?

Ketotifen is a type of drug known as an antihistamine. Ketotifen works by binding to histamine H-1 receptors on various cells throughout the body, including white blood cells. By blocking histamine, it prevents symptoms such as sneezing, itchiness, redness, inflammation, and runny nose.

Ketotifen is used to treat the following:

  • Allergic conjunctivitis
  • Allergic rhinitis

How should I take ketotifen?

Ketotifen is available as an oral tablet, syrup, drops, and ophthalmic solution. The oral tablet, syrup, and drops should be taken by mouth. The tablet should be swallowed whole without chewing or crushing it.

The liquid preparations should be measured using the included medical-grade measuring cup or dropper. Do not use a regular household spoon, as this may not measure the correct dose.

The ophthalmic solution should be instilled into the eye(s) without touching the tip of the bottle. Always cover the nozzle after each use and during storage. If you wear contact lenses, remove the lenses prior to instilling the drops.

How do I store ketotifen?

This drug should be stored at room temperature (<30°C) and be protected from light and moisture. Do not freeze this product. Always check the label before using this product. For safety, keep out of the reach of children and pets.

Do not use if the printed expiration date has passed, the product seal has been broken, or the product has changed in color, odor, or consistency.

Do not dispose of this product by pouring it down the drain, toilet, or into the environment. Ask your pharmacist regarding the proper way and location of disposal.

Precautions & Warnings

What should I know before using ketotifen?

Before using this medication, inform your doctor if:

  • You have ever had an allergic reaction to ketotifen
  • You have a history of allergy to other medications, food, or other substances
  • You are taking other medications
  • You have underlying health conditions

Is it safe during pregnancy or breastfeeding?

Ketotifen is a pregnancy category C drug. There are no adequate and well-controlled studies using ketotifen in pregnant women. This drug should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus, as determined by your doctor.

This drug may be excreted in breast milk. This drug should be used while breastfeeding only if the potential benefit justifies the potential risk to the child, as determined by your doctor.

Side Effects

What side effects can occur when using ketotifen?

All drugs have the potential to elicit side effects even with normal use. Many side effects are dose-related and will resolve when it is adjusted or at the end of therapy.

Potential side effects while using this drug include:

  • Drowsiness
  • Dizziness
  • Insomnia
  • Agitation, irritability
  • Nervousness
  • Eye irritation
  • Blurred vision
  • Dry mouth or eyes
  • Weight gain

Severe adverse reactions:

  • Skin rash
  • Redness
  • Blistering of the lips, eyes, or mouth
  • Fever
  • Chills
  • Headache
  • Jaundice
  • Seizure

You may experience some, none, or other side effects not mentioned above. If you experience serious adverse reactions, you must stop taking the drug immediately. If you have any concerns about a side effect or it becomes bothersome, consult your doctor or pharmacist.

Interactions

What drugs may interact with ketotifen?

This drug may interact with other medications. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist.

Known drugs and their interactions with medication include:

  • Sedatives
    • Increased symptoms of drowsiness
  • Hypnotics
    • Increased symptoms of drowsiness
  • Other antihistamines
    • Increased symptoms of drowsiness
  • Oral antidiabetics
    • Reduced platelet count (potentially fatal)

If you experience an adverse drug interaction, stop taking this drug and continue taking your other medication. Inform your doctor immediately to reevaluate your treatment plan. Your dose may need to be adjusted, substituted with another drug, or discontinue using the drug.

Does food or alcohol interact with ketotifen?

There are no known food interactions with ketotifen. However, it is best to take this medication with meals. Do not take ketotifen with alcohol as it may potentiate the effects of drowsiness and CNS depression.

Inform your doctor or pharmacist if you have any concerns regarding food-drug interactions.

What health conditions may interact with ketotifen?

This drug should be taken with caution if you have any of the following conditions or risk factors:

  • History of epilepsy
  • Diabetes mellitus

Inform your doctor or pharmacist if you have any concerns regarding specific health conditions.

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult your doctor or pharmacist before using ketotifen.

What is the dose of ketotifen for an adult?

For treating allergic rhinitis

  • Oral preparations: Take 1 mg two times a day, increasing the dose up to 2 mg if needed.
    • Alternatively, take 0.5 to 1 mg at night for the first few days of treatment, to minimized drowsiness.

For treating allergic conjunctivitis

  • Ophthalmic drops: Instill 1 drop into the conjunctival sac of the affected eye(s) two times a day.

What is the dose of ketotifen for a child?

For treating allergic rhinitis

  • For children 3 years and above: The same as the adult dose.

For treating allergic conjunctivitis

  • For children 3 years and above: The same as the adult dose.

How is ketotifen available?

This drug is available in the following brands, dosage forms, and strengths:

  • Azimef syrup 1 mg/5 mL
  • Zadec oral infant drops solution 1 mg/ mL
  • Zaditen tablet 1 mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of this drug, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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