Disclaimer
This drug or supplement is not currently available for sale or use in the Philippines. The information provided here is for informational purposes only.
Uses
What is androstenetrione used for?
Androstenetrione is part of a class of drugs known as anabolic steroids. Anabolic steroids, or steroids, are synthetic hormones that mimic or promote testosterone function. These steroids are different from corticosteroids and are used to building muscle, increasing testosterone, and promoting the development of male sex characteristics.
While anabolic steroids are prescribed to treat hormonal issues such as delayed or late-onset puberty, steroids are often misused by male competitive athletes and body builders in order to improve their performance and aesthetics. In these cases, the unauthorized use of steroids or other banned substances to gain a competitive edge is known as “doping.”
Alternative names for androstenetrione are 4-AT and 6-oxo. Manufacturers advertise it as a natural testosterone booster and irreversible aromatase inhibitor that prevents the conversion of testosterone to estradiol (estrogen).
However, an 8-week study done to determine the effects of 6-oxo showed that it had no effect on body composition while it incompletely inhibited aromatase and increased endogenous levels of testosterone and dihydrotestosterone (DHT).
How should I take androstenetrione?
Androstenetrione is manufactured as an oral capsule. It is no longer available on the market due to FDA violations and health concerns.
How do I store androstenetrione?
This drug should be stored at room temperature (<30°C) and be protected from moisture. For safety, keep out of the reach of children and pets.
Always check the label before using this product. Do not use if the printed expiration date has passed, the product seal has been broken, or the product has changed in color, odor, or consistency.
Do not dispose of this product by pouring it down the drain, toilet, or into the environment. Ask your pharmacist regarding the proper way and location of disposal.
Precautions & Warnings
What should I know before using androstenetrione?
Anabolic steroids, including androstenetrione, are associated with many negative side effects. These effects include mental and behavioral changes such as aggression (“roid rage”), paranoia, irritability, delusions, and impaired judgement. Physical changes also occur. While anabolic steroids do increase testosterone levels and build muscle, these effects are not permanent and long-term use can result in serious health problems.
Before using this medication, inform your doctor if:
- You have ever had an allergic reaction to androstenetrione or other anabolic steroids
- You have a history of allergy to other medications, food, or other substances.
- You are taking other medications, especially other anabolic steroids.
- You have underlying health conditions.
Is it safe during pregnancy or breastfeeding?
In general, anabolic steroids should not be used by women, especially during pregnancy or while breastfeeding. Female fetuses that are exposed to high levels of testosterone while in the womb may undergo virilization, developing masculine physical characteristics upon birth.
Side Effects
What side effects can occur when using androstenetrione?
All drugs have the potential to elicit side effects even with normal use. Many side effects are route and dose-related and will likely resolve when it is adjusted or at the end of therapy.
Potential side effects while using this drug include:
- Mood swings
- Mental changes
- Kidney injury or failure
- Liver damage
- Cardiomegaly
- Hypertension
- Elevated lipid profile
- Increased risk of blood clots and stroke
- Shrinking testicles (in males)
- Decreased fertility
- Hair loss or male-pattern baldness
- Gynecomastia
- Hirsutism (in women)
- Decreased breast size (in women)
- Amenorrhea
- Enlarged clitoris
- Deepened voice
- Stunted growth
- Acne
Withdrawal or end-of-use symptoms include:
- Fatigue
- Restlessness
- Loss of appetite
- Insomnia
- Decreased libido
- Steroid cravings
- Depression
You may experience some, none, or other side effects not mentioned above. If you have any concerns about a side effect or it becomes bothersome, consult your doctor or pharmacist.
Interactions
What drugs may interact with androstenetrione?
This drug may interact with other medications. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and inform your doctor and pharmacist.
If you experience an adverse drug interaction, stop taking this drug. Inform your doctor immediately to reevaluate your treatment plan. Your dose may need to be adjusted, substituted with another drug, or discontinue using the drug.
Does food or alcohol interact with androstenetrione?
There are no notable interactions with food or alcohol.
Inform your doctor or pharmacist if you have any concerns regarding food-drug interactions.
What health conditions may interact with androstenetrione?
This drug should be taken with caution if you have any of the following conditions or risk factors:
- Pregnancy
- PCOS
- Dyslipidemia
- Heart disease
- Hypertension
- Diabetes mellitus
Inform your doctor or pharmacist if you have any concerns regarding specific health conditions.
Dosage
The information provided is not a substitute for any medical advice. You should ALWAYS consult your doctor or pharmacist before using androstenetrione.
What is the dose of androstenetrione for an adult?
The recommended dose has not been established. Consult your doctor for alternatives and more information.
What is the dose of androstenetrione for a child?
The recommended dose has not been established. Consult your child’s doctor for alternatives and more information.
What should I do in case of an emergency or overdose?
In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.
What should I do if I miss a dose?
If you miss a dose of this drug, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.
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