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Zytee RB®

Written by Stephanie Nera, RPh, PharmD · Pharmacology

Updated Dec 03, 2020


Zytee RB® is mainly indicated to treat:

  • Glossitis
  • Stomatitis
  • Mouth ulcers
  • Other inflammatory lesions of the mouth
  • Denture irritation

How should I take Zytee RB®?

Zytee RB® is available as an oral gel. Wash your hands thoroughly before and after application. Apply 1 to 2 pea-sized amounts of Zytee RB® onto your index finger and gently rub it onto the affected areas of the gum, inner cheeks, or mouth.

Do not apply the gel to broken skin or open wounds. Do not put your dentures of braces back on for about an hour and a half after applying the gel. If symptoms do not improve after one week, discontinue using Zytee RB® and consult your doctor.

How do I store Zytee RB®?

This drug should be stored at room temperature (20-25°C) and be protected from light and moisture. Do not store it in the refrigerator or freezer.  For safety, keep out of the reach of children and pets.

Always check the label before using this product. Do not use if the printed expiration date has passed, the product seal has been broken, or the product has changed in color, odor, or consistency.

Do not dispose of this product by pouring it down the drain, toilet, or into the environment. Ask your pharmacist regarding the proper way and location of disposal.

Precautions & Warnings

What should I know before using Zytee RB®?

Before using this medication, inform your doctor if:

  • You have ever had an allergic reaction to Zytee RB® or similar products.
  • You have a history of allergy to other medications, food, or other substances.
  • You are taking other medications.
  • You are pregnant or breastfeeding.
  • You have any underlying health conditions

Is it safe during pregnancy or breastfeeding?

There isn’t enough information about the safety of using Zytee RB® during pregnancy and breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Zytee RB®.

Side Effects

All drugs have the potential to elicit side effects even with normal use. Many side effects are dose-related and will resolve when it is adjusted or at the end of therapy.

Potential side effects while using this drug include:

  • Restlessness
  • Allergic contact dermatitis
  • Convulsions
  • Paralysis of respiratory muscle
  • Vomiting
  • Coma

You may experience some, none, or other side effects not mentioned above. If you have any concerns about a side effect or it becomes bothersome, consult your doctor or pharmacist.


Zytee RB® may interact with other medications. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and inform your doctor and pharmacist.

If you experience an adverse drug interaction, stop taking this drug and continue taking your other medication. Inform your doctor immediately to reevaluate your treatment plan. Your dose may need to be adjusted, substituted with another drug, or discontinue using the drug.

Does food or alcohol interact with Zytee RB®?

Zytee RB® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Avoid eating or drinking for 1 to 2 hours after applying the gel.

Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Zytee RB®?

Zytee RB® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.


The information provided is not a substitute for any medical advice. You should ALWAYS consult your doctor or pharmacist before using Zytee RB®.

What is the dose of Zytee RB® for an adult?

The recommended dose is 1 to 2 pea-sized amounts applied gently onto the affected areas. May be repeated every 3 to 4 hours as required or as advised by your doctor.

What is the dose of Zytee RB® for a child?

Zytee RB® is not recommended for use in children under 12 years and the recommended dose has not been established. Consult with a doctor or pharmacist for alternatives and more information.

How is Zytee RB® available?

Zytee RB® is available in the following dosage forms and strengths:

  • Zytee RB® gel 10ml

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Zytee RB®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.


Hello Health Group does not provide medical advice, diagnosis or treatment.

Written by

Stephanie Nera, RPh, PharmD


Updated Dec 03, 2020

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