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Written by Stephanie Nera, RPh, PharmD · Pharmacology

Updated Sep 08, 2020


Bugleweed (Lycopus virginicus) is an herb that in the same family as mint and sage. It is commonly found in Eastern North American states. The leaves have pointed, serrated edges and are colored green and reddish-brown with small white flower clusters at the base of the leaves on the stem.

Traditionally, bugleweed was used to treat coughs and induce sedation. In modern times, bugleweed is used as a supplemental treatment for mild cases of hyperthyroidism and goiter.

Bugleweed can be used as supplemental treatment for the following:

  • Hyperthyroidism
  • Toxic goiter
  • Grave’s disease
  • Other hormonal imbalances
  • Contraception
  • How does it work?

    Active compounds found in bugleweed include phenolic compounds. The exact mechanisms are not known; however, studies have shown that extracts of L. virginicus inhibit iodine metabolism and thyroxine release in the thyroid. This can explain its use in treating thyroid disorders.

    It may also possess antigonadotrophic, anti-prolactin, and anti-glucagon effects. These properties make it a potential contraceptive and blood sugar regulator.

    Precautions & Warnings

    Herbal supplements are generally safe to take in moderate amounts as directed by a health professional. However, because most herb and food supplements are not approved by the FDA for treating and preventing specific diseases, recommended daily values are not always established.

    Despite being advertised as “all-natural” or “safe,” natural or food supplements must be treated as conventional medication. Certain herbal preparations can interact with other medications you are taking, increasing the risk of adverse drug reactions and toxicity.

    Before using this medication, inform your doctor if:

    • You have ever had an allergic reaction to Bugleweed or other supplements.
    • You have a history of allergy to other medications, food, or other substances.
    • You are taking other medications.
    • You have underlying health conditions.

    Is it safe during pregnancy or breastfeeding?

    There is insufficient data regarding the use and safety of this supplement during pregnancy. This supplement should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus, as determined by your doctor.

    It is not known if the active compounds are excreted into breast milk. This supplement should be used while breastfeeding only if the potential benefit justifies the potential risk to the child, as determined by your doctor.

    Side Effects

    All supplements have the potential to elicit side effects even with normal use. Many side effects are dose-related and will resolve when it is adjusted or at the end of therapy.

    Potential side effects while using this supplement include:

    • Gastrointestinal discomfort
    • Allergic reaction
    • Headache
    • Low levels of thyroid hormone
    • Changes menstrual pattern and flow

    You may experience some, none, or other side effects not mentioned above. If you have any concerns about a side effect or it becomes bothersome, consult your doctor or pharmacist.


    To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and inform your doctor and pharmacist.

    The liquid extract preparation of this medication may contain alcohol. Avoid taking the following together with this preparation:

    • Antihistamines
    • Sedatives
    • CNS depressants

    If you experience an adverse drug interaction, stop taking this drug and continue taking your other medication. Inform your doctor immediately to reevaluate your treatment plan. Your dose may need to be adjusted, substituted with another drug, or discontinue using the drug.

    Does food or alcohol interact with bugleweed?

    This medication may be taken with or without food. If you experience any gastrointestinal discomfort, taking this medication with meals may prevent this symptom. It is important to drink enough water while taking this medication.

    The liquid extract preparation of this medication may contain alcohol thus alcohol consumption should be limited to prevent intoxication, especially in children or adults who need to drive or operate machinery.

    Inform your doctor or pharmacist if you have any concerns regarding food-drug interactions.

    What health conditions may interact with bugleweed?

    This supplement should be taken with caution if you have any of the following conditions or risk factors:

    • Allergy to any of the ingredients

    Inform your doctor or pharmacist if you have any concerns regarding specific health conditions.


    The information provided is not a substitute for professional medical advice. You should ALWAYS consult your doctor or pharmacist before using bugleweed.

    What is the dose of bugleweed for an adult?

    The recommended dosage of this drug has not been established for treating any specific disease or condition. Consult a doctor for the appropriate indication and dosage.

    What is the dose of bugleweed for a child?

    This supplement is not recommended for use in children and the recommended dose has not been established. Consult a doctor or pharmacist for alternatives and more information.

    How is bugleweed available?

    This supplement is available in the following dosage forms:

    • Liquid extract
    • Tea
    • Capsule

    What should I do in case of an emergency or overdose?

    In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

    What should I do if I miss a dose?

    If you miss a dose of this supplement, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.


    Hello Health Group does not provide medical advice, diagnosis or treatment.

    Written by

    Stephanie Nera, RPh, PharmD


    Updated Sep 08, 2020

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