Does food or alcohol interact with aminophylline?
This drug may interact with food or herbal supplements. St. John’s wort may increase the clearance of aminophylline. Grilled or char-broiled food (i.e. barbeque) can reduce the half-life of aminophylline by 50%, making it less effective.
You should not take this drug with alcohol as it increases the clearance of aminophylline, making it less effective.
Inform your doctor or pharmacist if you have any concerns regarding food-drug interactions.
What health conditions may interact with aminophylline?
This drug should be taken with caution if you have any of the following conditions:
- Seizures
- Heart disease
- An overactive or underactive thyroid gland
- High blood pressure
- Liver disease
- History of alcohol abuse
Inform your doctor or pharmacist if you have any concerns regarding specific health conditions.
Dosage
The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using aminophylline.
What is the dose of aminophylline for an adult?
Asthma, bronchitis, and emphysema
Adults, teenagers, and children above 1 year of age weighing more than 45 kilograms (kg)
At first, 380 milligrams (mg) per day, divided and given every 6 to 8 hours. Your doctor may adjust your dose as needed. However, the total dose is usually not more than 760 mg per day.
Older adults
The dose must be determined by your doctor. However, the total dose is usually not more than 507 milligrams per day, divided and given every 6 to 8 hours.
What is the dose of aminophylline for a child?
Asthma, bronchitis, and emphysema
Adults, teenagers, and children above 1 year of age weighing more than 45 kilograms (kg)
At first, 380 milligrams (mg) per day, divided and given every 6 to 8 hours. Your doctor may adjust your dose as needed. However, the total dose is usually not more than 760 mg per day.
Children and teenagers 1 to 15 years of age weighing less than 45 kilograms (kg)
The dose is based on body weight and must be determined by your doctor. At first, the dose is 15.2 to 17.7 milligrams (mg) per kg of body weight per day, divided and given every 4 to 6 hours. Your doctor may adjust your dose as needed. However, the total dose is usually not more than 25.3 mg per kg of body weight per day or 760 mg per day.
Infants younger than 1 year of age
Use and dose must be determined by your doctor.
How is aminophylline available?
Aminophylline is available in the following brands, dosage forms, and strengths:
- Amilin tablet 10 mg
- Aminosol solution for injection 25 mg/mL
- Phil Pharmawealth solution for injection 25 mg/mL
What should I do in case of an emergency or overdose?
In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room. Symptoms over overdose may include:
- Tachycardia
- Hypotension
- Seizures, convulsions
- Somnolence
- Loss of consciousness
- Fever
- Irritability
- Hypokalemia
- Hyperglycemia
- Hyperthermia
- Respiratory alkalosis
- Metabolic acidosis
- Rhabdomyolysis
Treatment is symptomatic and supportive. Activated charcoal, diazepam, potassium chloride, propranolol, and fluid with electrolytes should be used to treat the pertinent symptoms.
What should I do if I miss a dose?
If you miss a dose of this drug, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.
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