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Aminophylline is used to prevent and treat wheezing, shortness of breath, and difficulty breathing caused by asthma, chronic bronchitis, emphysema, and other respiratory diseases. It relaxes and opens air passages in the lungs, making it easier to breathe.
Aminophylline is sometimes used to treat breathing problems in premature infants. Talk to your doctor about the possible risks of using this drug for your baby’s condition.
Aminophylline is available as an oral tablet and solution for injection. The oral tablet should be taken by mouth without chewing or crushing it. The tablets can be taken with or without food, followed by a glass of water.
The solution for injection should be administered by a licensed health professional.
This drug should be stored at room temperature (20-25°C) and be protected from light and moisture. Do not freeze this product. Always check the label before using this product. For safety, keep out of the reach of children and pets.
Do not use if the printed expiration date has passed, the product seal has been broken, or the product has changed in color, odor, or consistency.
Do not dispose of this product by pouring it down the drain, toilet, or into the environment. Ask your pharmacist regarding the proper way and location of disposal.
Before using this medication, inform your doctor if:
This drug is a pregnancy category C drug. There are no adequate and well-controlled studies using pentoxifylline in pregnant women. This drug should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus, as determined by your doctor.
This drug is excreted in breast milk. This drug should be used while breastfeeding only if the potential benefit justifies the potential risk to the child, as determined by your doctor.
All drugs have the potential to elicit side effects even with normal use. Many side effects are dose-related and will resolve when it is adjusted or at the end of therapy.
Potential side effects while using this drug include:
Rare, serious adverse reactions:
You may experience some, none, or other side effects not mentioned above. If you experience serious adverse reactions, you must stop taking the drug immediately. If you have any concerns about a side effect or it becomes bothersome, consult your doctor or pharmacist.
Aminophylline may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.
Products may interact with this drug, such as:
If you experience an adverse drug interaction, stop taking this drug and continue taking your other medication. Inform your doctor immediately to reevaluate your treatment plan. Your dose may need to be adjusted, substituted with another drug, or discontinue using the drug.
This drug may interact with food or herbal supplements. St. John’s wort may increase the clearance of aminophylline. Grilled or char-broiled food (i.e. barbeque) can reduce the half-life of aminophylline by 50%, making it less effective.
You should not take this drug with alcohol as it increases the clearance of aminophylline, making it less effective.
Inform your doctor or pharmacist if you have any concerns regarding food-drug interactions.
This drug should be taken with caution if you have any of the following conditions:
Inform your doctor or pharmacist if you have any concerns regarding specific health conditions.
The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using aminophylline.
Asthma, bronchitis, and emphysema
Adults, teenagers, and children above 1 year of age weighing more than 45 kilograms (kg)
At first, 380 milligrams (mg) per day, divided and given every 6 to 8 hours. Your doctor may adjust your dose as needed. However, the total dose is usually not more than 760 mg per day.
Older adults
The dose must be determined by your doctor. However, the total dose is usually not more than 507 milligrams per day, divided and given every 6 to 8 hours.
Asthma, bronchitis, and emphysema
Adults, teenagers, and children above 1 year of age weighing more than 45 kilograms (kg)
At first, 380 milligrams (mg) per day, divided and given every 6 to 8 hours. Your doctor may adjust your dose as needed. However, the total dose is usually not more than 760 mg per day.
Children and teenagers 1 to 15 years of age weighing less than 45 kilograms (kg)
The dose is based on body weight and must be determined by your doctor. At first, the dose is 15.2 to 17.7 milligrams (mg) per kg of body weight per day, divided and given every 4 to 6 hours. Your doctor may adjust your dose as needed. However, the total dose is usually not more than 25.3 mg per kg of body weight per day or 760 mg per day.
Infants younger than 1 year of age
Use and dose must be determined by your doctor.
Aminophylline is available in the following brands, dosage forms, and strengths:
In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room. Symptoms over overdose may include:
Treatment is symptomatic and supportive. Activated charcoal, diazepam, potassium chloride, propranolol, and fluid with electrolytes should be used to treat the pertinent symptoms.
If you miss a dose of this drug, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.
Use this calculator to check your body mass index (BMI) and find out if you're at a healthy weight. You can also use this tool to check your child's BMI.
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Hello Health Group does not provide medical advice, diagnosis or treatment.
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