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Adrenal extract

Uses|Precautions & Warnings|Side Effects|Interactions|Dosage


What is adrenal extract used for?

Adrenal extracts are, as the name suggests, extracts derived from the adrenal glands. The adrenal glands used to make extracts are typically from bovine (beef) cattle sources. Extracts can be made using the whole adrenal gland or just the adrenal cortex.

The adrenal glands are endocrine organs, producing and releasing many essential hormones such as cortisol, aldosterone, steroids, norepinephrine, and epinephrine directly into the bloodstream.

Adrenal extract has the following uses:

  • Treat “adrenal fatigue”
  • Boost energy
  • Reduce inflammation

How does it work?

The exact mechanism of action of adrenal extracts are not known. Alternative medicine promotes the use of extracts to treat and prevent “adrenal fatigue.” However, this condition and the use of adrenal gland extracts have not been validated by conventional medicine.

Consult your doctor or pharmacist for more information.

Precautions & Warnings

What should I know before using adrenal extract?

Herbal supplements are generally safe to take in moderate amounts as directed by a health professional. However, because most herb and food supplements are not approved by the FDA for treating and preventing specific diseases, recommended daily values are not always established.

Despite being advertised as “all-natural” or “safe,” natural or food supplements must be treated as conventional medication. Certain herbal preparations can interact with other medications you are taking, increasing the risk of adverse drug reactions and toxicity.

Before using this medication, inform your doctor if:

  • You have ever had an allergic reaction to adrenal extract or other supplements.
  • You have a history of allergy to other medications, food, or other substances.
  • You are taking other medications.
  • You have underlying health conditions.
  • You have dietary restrictions, such as being vegetarian or avoid meat for religious reasons.

Is it safe during pregnancy or breastfeeding?

There is insufficient data regarding the use and safety of this supplement during pregnancy. This supplement should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus, as determined by your doctor.

There is no data available regarding the effect of adrenal extracts on breast milk. This supplement should be used while breastfeeding only if the potential benefit justifies the potential risk to the child, as determined by your doctor.

Side Effects

What side effects can occur from adrenal extract?

All supplements have the potential to elicit side effects even with normal use. Many side effects are dose-related and will resolve when it is adjusted or at the end of therapy.

Potential side effects while using this supplement include:

  • Gastrointestinal discomfort
  • Allergic reaction

You may experience some, none, or other side effects not mentioned above. If you have any concerns about a side effect or it becomes bothersome, consult your doctor or pharmacist.


What drugs may interact with adrenal extract?

To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and inform your doctor and pharmacist.

The liquid extract preparation of this medication may contain alcohol. Avoid taking the following together with this preparation:

  • Antihistamines
  • Sedatives
  • CNS depressants

If you experience an adverse drug interaction, stop taking this drug and continue taking your other medication. Inform your doctor immediately to reevaluate your treatment plan. Your dose may need to be adjusted, substituted with another drug, or discontinue using the drug.

Does food or alcohol interact with adrenal extract?

This medication may be taken with or without food. If you experience any gastrointestinal discomfort, taking this medication with meals may prevent this symptom. It is important to drink enough water while taking this medication.

The liquid extract preparation of this medication may contain alcohol thus alcohol consumption should be limited to prevent intoxication, especially in children or adults who need to drive or operate machinery.

Inform your doctor or pharmacist if you have any concerns regarding food-drug interactions.

What health conditions may interact with adrenal extract?

This supplement should be taken with caution if you have any of the following conditions or risk factors:

  • Allergy to any of the ingredients

Inform your doctor or pharmacist if you have any concerns regarding specific health conditions.


The information provided is not a substitute for professional medical advice. You should ALWAYS consult your doctor or pharmacist before using adrenal extracts.

What is the dose of adrenal extract for an adult?

The recommended dosage of this drug has not been established for treating any specific disease or condition. Consult a doctor for the appropriate indication and dosage.

What is the dose of adrenal extract for a child?

This supplement is not recommended for use in children and the recommended dose has not been established. Consult a doctor or pharmacist for alternatives and more information.

How is adrenal extract available?

This supplement is available in the following dosage forms:

  • Liquid extract
  • Capsule

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of this supplement, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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Written by Stephanie Nicole Nera, RPh, PharmD Updated Aug 18, 2020