Neuropathic or nerve pain is a type of pain that a lot of people misunderstand. One reason behind this is that nerve pain symptoms can vary from person to person, or even mimic symptoms of other conditions.
Neuropathic or nerve pain is a type of pain that a lot of people misunderstand. One reason behind this is that nerve pain symptoms can vary from person to person, or even mimic symptoms of other conditions.

If left untreated, it can severely impact a person’s quality of life. This is why if you feel any nerve pain symptoms, it’s always a good idea to talk to your doctor.
Nerve pain is defined as pain that’s caused by a lesion of the somatosensory nervous system1. It can affect a person’s hands and feet, as well as other parts of the body. It is a chronic condition, lasting 6 months or more.
Nerve pain may feel different compared to other types of pain, such as muscle pain. The usual symptoms include the following2, 3:
Take note however that having the symptoms above doesn’t necessarily mean you have nerve pain. It is best to consult your doctor and avoid self-diagnosing.
Neuropathic pain is caused by neuropathy, or damage to the nerves. There are two types of neuropathy: peripheral neuropathy and central neuropathy.
Peripheral neuropathy affects the peripheral nervous system or all of the nerves outside the brain and spinal cord. On the other hand, central neuropathy affects nerves in a person’s central nervous system, which is made up of the brain and spine.
Some of the causes of peripheral neuropathy are3:
Central neuropathic pain may be the result of4:
Nerve pain gets worse over time if left untreated. It’s common for people with untreated nerve pain to experience anxiety, depression, and lack of sleep due to prolonged duration of their symptoms5.
Diabetic ulcers in particular can be dangerous. Patients might not even be aware they have them because of the numbness brought about by nerve pain. Having diabetes also means that wounds don’t heal as quickly, so a patient can have an open sore which is prone to infection and gangrene.
Treatment for nerve pain symptoms vary depending on the underlying cause. Some doctors might prescribe oral medications in order to help patients manage their pain6. Topical medications can also be prescribed by doctors depending on what type of neuropathic pain the patient has7.
Aside from medications, healthy lifestyle habits such as exercise, eating healthy foods, and maintaining a healthy weight may be recommended6. If the patient smokes, doctors will also suggest that they quit as soon as possible. This is because smoking can constrict blood vessels and make symptoms worse.
Patients with nerve pain symptoms should do their best to take their medication as prescribed by their doctor and maintain a healthy lifestyle. This way, they can better manage their neuropathy and prevent it from affecting their quality of life.

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1 International Association for the Study of Pain (IASP). IASP Terminology, https://www.iasp-pain.org/Education/Content.aspx?ItemNumber=1698, Accessed January 6, 2023
2 Gilron I et al. (2006). Neuropathic pain: a practical guide for the clinician, Canadian Medical Association Journal, 175(3):265-75, https://doi.org/10.1503/cmaj.060146. Accessed January 6, 2023
3 Cleveland Clinic, Neuropathy (Peripheral Neuropathy), https://my.clevelandclinic.org/health/diseases/14737-neuropathy, Accessed January 6, 2023
4 Watson, J., Sandroni, P. (2016). Central Neuropathic Pain Syndromes, Symposium on Pain Medicine 91(3):372-85, https://www.mayoclinicproceedings.org/article/S0025-6196(16)00073-2/fulltext. Accessed January 6, 2023
5 Nicholson B, Verma S. (2004). Comorbidities in Chronic Neuropathic Pain, Pain Medicine 5(suppl.1):S9-27., 10.1111/j.1526-4637.2004.04019.x. Accessed January 6, 2023
6 Finnerup NB, Attal N, Haroutounian S, McNicol E, Baron R, Dworkin RH, Gilron I, Haanpää M, Hansson P, Jensen TS, Kamerman PR, Lund K, Moore A, Raja SN, Rice AS, Rowbotham M, Sena E, Siddall P, Smith BH, Wallace M. (2015). Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis, The Lancet Neurology 14(2):162-73. 10.1016/S1474-4422(14)70251-0. Accessed January 6, 2023
7 Bates, D., et al. (2019). A Comprehensive Algorithm for Management of Neuropathic Pain, Pain Medicine 20(Suppl 1): S2-S12, https://doi.org/10.1093/pm/pnz075. Accessed January 6, 2023
8 Centers for Disease Control and Prevention, Diabetes (What is Diabetes?), https://www.cdc.gov/diabetes/basics/diabetes.html#:~:text=Diabetes%20is%20a%20chronic%20(long,your%20pancreas%20to%20release%20insulin. Accessed January 6, 2023
9 Centers for Disease Control and Prevention, Diabetes (Prevent Diabetes Complications), https://www.cdc.gov/diabetes/managing/problems.html#:~:text=Common%20diabetes%20health%20complications%20include,how%20to%20improve%20overall%20health., Accessed January 6, 2023
10 National Cancer Institute, What Is Cancer?, https://www.cancer.gov/about-cancer/understanding/what-is-cancer#:~:text=Pittsburgh%20Cancer%20Institute-,The%20Definition%20of%20Cancer,up%20of%20trillions%20of%20cells., Accessed January 6, 2023
11 Centers for Disease Control and Prevention, HIV (About HIV), https://www.cdc.gov/hiv/basics/whatishiv.html#:~:text=HIV%20(human%20immunodeficiency%20virus)%20is,care%2C%20HIV%20can%20be%20controlled., Accessed January 6, 2023
12 National Institute of General Medical Sciences, What is physical trauma?, https://www.nigms.nih.gov/education/fact-sheets/Pages/physical-trauma.aspx#:~:text=Physical%20trauma%20is%20a%20serious,usually%20creating%20an%20open%20wound., Accessed January 6, 2023
Current Version
06/19/2023
Written by Mia Dacumos, MD
Updated by: Mia Labrador, MD
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