Before we discuss the symptoms of thalassemia, let’s first talk about its types, which could either point to the part of hemoglobin affected or the severity of the symptoms.
You see, hemoglobin is made up of two proteins: alpha and beta. If there’s an issue in the gene responsible for alpha protein, then it’s alpha thalassemia. Likewise, if the issue lies within the gene making the beta protein, it’s called beta thalassemia.
Now, alpha and beta can be further subdivided into thalassemia minor and major. Inheriting a gene defect from both parents leads to thalassemia major; inheriting a gene defect from only one parent results in thalassemia minor.
If you hear the term intermedia, it refers to a type of thalassemia that’s somewhere between minor and major.
Often, people with thalassemia minor have mild symptoms or are only carriers: they have the faulty gene, but they don’t have symptoms. On the other hand, individuals with thalassemia major may experience severe symptoms.
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