Prevacid

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Update Date 11/05/2020 . 6 mins read
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Uses

What is Prevacid® (lansoprazole) used for?

Prevacid® is a proton pump inhibitor commonly used for treating or preventing hyperacidity and stomach diseases such as stomach and intestinal ulcers, erosive esophagitis (damage to the esophagus from stomach acid), and Zollinger-Ellison syndrome.

Prevacid® is used to treat frequent heartburn that happens two or more days per week.

Prevacid® is not used for immediate relief of heartburn symptoms.

How should I take Prevacid® (lansoprazole)?

Use Prevacid® exactly as directed on the label, or as prescribed by your doctor. Do not use it in larger or smaller amounts or for longer than recommended.

Prevacid® should be taken in the morning before you eat breakfast or your first meal.

Do not crush, chew, break, or open a delayed-release capsule. Swallow it whole.

Do not break, chew, or cut an orally disintegrating tablet, and do not swallow it whole. Allow the tablet to dissolve in your mouth without chewing. If desired, you may drink liquid to help swallow the dissolved tablet.

If you are unable to dissolve the orally disintegrating tablet in your mouth:

  • Place a 15-milligram tablet into an oral syringe and draw 4 milliliters of water into the syringe. If using a 30-milligram tablet, draw 10 milliliters of water into the syringe.
  • Shake the syringe gently until the tablet is dispersed. Then empty the syringe into your mouth within 15 minutes after mixing. Refill the syringe with water, shake gently, and empty into your mouth.
  • The Prevacid® disintegrating tablet may also be given through a nasogastric (NG) feeding tube as follows: Disperse the tablet in an oral syringe as directed above. Then inject the mixture through the NG tube into the stomach within 15 minutes. Flush the tube with 5 more milliliters of water to wash the contents down.

Take this medicine for the full prescribed length of time. Your symptoms may improve before your condition is completely treated.

Prevacid® should be taken only once daily for 14 days. Do not take more than one tablet every 24 hours. It may take up to 4 days for full effect. Allow at least 4 months to pass before you start another 14-day treatment with Prevacid®.

How do I store Prevacid® (lansoprazole)?

Prevacid® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Prevacid® in the bathroom or the freezer. There may be different brands of Prevacid® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Prevacid® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Prevacid® (lansoprazole)?

Prevacid® is not for immediate relief of heartburn symptoms. Heartburn is often confused with the first symptoms of a heart attack. Seek emergency medical attention if you have chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, and a general ill feeling.

If you also take sucralfate, avoid taking it at the same time you take Prevacid®. Sucralfate can make it harder for your body to absorb lansoprazole. Wait at least 30 minutes after taking this medicine before you take sucralfate.

If you use Prevacid® for longer than 3 years, you could develop a vitamin B-12 deficiency. Talk to your doctor about how to manage this condition if you develop it.

Do not use Prevacid® without the advice of a doctor if you have:

  • Trouble or pain with swallowing
  • Bloody or black stools
  • Vomit that looks like blood or coffee grounds
  • Heartburn that has lasted for over 3 months
  • Frequent chest pain, heartburn with wheezing
  • Unexplained weight loss
  • Nausea or vomiting
  • Stomach pain
  • An electrolyte imbalance or metabolic disorder

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using Prevacid® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Prevacid®. Prevacid® is pregnancy risk category B, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk
  • B=No risk in some studies
  • C=There may be some risk
  • D=Positive evidence of risk
  • X=Contraindicated
  • N=Unknown

Side effects

What side effects can occur from Prevacid® (lansoprazole)?

Get emergency medical help if you have signs of an allergic reaction to Prevacid® such as hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • Severe stomach pain
  • Diarrhea that is watery or bloody
  • Seizure (convulsions)
  • Kidney problems (urinating more or less than usual, blood in your urine, swelling, rapid weight gain)
  • Dizziness
  • Confusion
  • Fast or uneven heart rate
  • Tremors (shaking) or jerking muscle movements
  • Feeling jittery
  • Muscle cramps, muscle spasms in your hands and feet
  • Cough or choking feeling

Common side effects may include:

  • Nausea
  • Stomach pain
  • Diarrhea
  • Constipation
  • Headache

Call your doctor if your symptoms do not improve or if they get worse while you are taking this medicine. If you take Prevacid®, call your doctor if your heartburn gets worse over the 14-day treatment, or if you need treatment more than once every 4 months.

Interactions

What drugs may interact with Prevacid® (lansoprazole)?

Prevacid® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Products may interact with this drug, including:

  • Ampicillin
  • Atazanavir
  • Clarithromycin
  • Digoxin
  • Iron-containing medicines (ferrous fumarate, ferrous gluconate, ferrous sulfate, and others)
  • Ketoconazole
  • Methotrexate
  • Mycophenolate mofetil
  • Nelfinavir
  • Tacrolimus
  • Theophylline
  • Warfarin (Coumadin, Jantoven)

Does food or alcohol interact with Prevacid® (lansoprazole)?

Prevacid® may interact with food or alcohol by altering the way the drug works or increasing the risk for serious side effects. Do not eat or drink anything before taking this medication as it will render it less effective. It is best to take it at least 30 minutes before a meal. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Prevacid® (lansoprazole)?

Prevacid® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

These health conditions are:

  • Liver disease
  • Low levels of magnesium in your blood

Dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Prevacid® (lansoprazole).

What is the dose of Prevacid® (lansoprazole) for an adult?

Erosive esophagitis, gastric ulcer, Zollinger-Ellison syndrome:

30 mg once daily for up to 8 weeks

Duodenal ulcer:

30 mg once daily for 4-6 weeks

Elderly Patients and Patients with Impaired Hepatic Function: 

15 mg once daily.

Gastroesophageal reflux disease:

The recommended dose is 15 mg orally once a day. Therapy should be continued for up to 8 weeks.

Helicobacter pylori infection:

Triple therapy: Prevacid® 30 mg is combined with 1 g of amoxicillin and 500 mg of clarithromycin given orally every 12 hours for 10 or 14 days. Most investigators recommend treatment with at least two antimicrobial agents in order to achieve eradication. Monotherapy with Prevacid® is ineffective and should be avoided.

Dual therapy: Prevacid® 30 mg is combined with 1 gram of amoxicillin given orally every 8 hours for 14 days. Refer to the monograph for amoxicillin and/or clarithromycin for dosing information specific to elderly or renally-impaired patients.

For Prevacid IV administration

Prevacid IV is mixed with 0.9% sodium chloride (NaCl) solution or 5% dextrose in water and administered by IV drip twice daily. 

Alternatively, it is dissolved in 20 mL of 0.9% NaCl solution or 5% dextrose in water and administered slowly by IV injection twice daily.

What is the dose of Prevacid® (lansoprazole) for a child?

Gastroesophageal reflux disease:

Short term treatment of non-erosive GERD 

12 to 17 years: the recommended dose is 15 mg once daily for up to 8 weeks.

Erosive esophagitis:

1 to 11 years:

  • Less than or equal to 30 kg, the recommended dose is 15 mg once daily for up to 12 weeks.
  • Greater than 30 kg, the recommended dose is 30 mg once daily, up to 30 mg twice daily for up to 12 weeks.

12 to 17 years: the recommended dose is 30 mg once daily up to 8 weeks.

How is Prevacid® (lansoprazole) available?

Prevacid® is available in the following dosage forms and strengths:

  • Prevacid® FDT (fast-disintegrating tablet): 15 mg, 30 mg
  • Prevacid® IV (powder for injection): 30 mg vial

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Prevacid®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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