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Update Date 03/12/2020 . 4 mins read
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Disclaimer: this brand is not currently available for sale or use in the Philippines. The information provided here is for informational purposes only.

What is Novalgin® (metamizole, dipyrone) used for?

Novalgin® is generically known as metamizole or dipyrone. It is commonly used for many different types of pain such as tumors pain, pain after surgery, or injuries. It can also be given when other forms of treatment do not propose any effect. Novalgin® is not used for the treatment of mild pain (toothache, headache, menstrual pain).

How should I take Novalgin® (metamizole, dipyrone)?

Taking Novalgin® followings directions in the patient leaflet or of your doctor, including:

  • You should swallow the tablets as a whole.
  • Do not crush or chew it.
  • You should take Novalgin ®with a glass of water.
  • It should be taken with food.

How do I store Novalgin® (metamizole, dipyrone)?

Novalgin® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Novalgin® in the bathroom or the freezer. There may be different brands of Novalgin® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Novalgin® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Precautions & warnings

What should I know before using Novalgin® (metamizole, dipyrone)?

Before using Novalgin®, tell your doctor if:

  • You have allergies to Novalgin®, excipients using for a dosage form containing Novalgin®.
  • You have allergies to any other medicines, foods, dyes, preservatives, or animals.
  • You have any other health conditions.

Novalgin® should not be used in children under 6 years of age without the direction of a doctor.

Is it safe during pregnancy or breastfeeding?


Novalgin® should not be used during pregnancy, especially during the first 12 weeks and last 12 weeks because it may harm the fetus.


Avoid breastfeeding while you are using Novalgin®. After you stop using the medicine, it takes at least two days, to set off again to breastfeed.

Side effects

What side effects can occur from Novalgin® (metamizole, dipyrone)?

Novalgin® can cause the side effects. These are:

  • Nausea
  • Vomiting
  • Diarrhea
  • Pain and discomfort in the stomach
  • Drowsiness
  • Nervousness
  • Headache
  • Dizziness
  • Blood in the urine, change in color of urine
  • Skin rash
  • Itching
  • Swelling
  • Shortness of breath
  • Cold sweat drenching and others
  • Anemia
  • Agranulocytosis
  • Fever
  • Fatigue
  • Difficulty swallowing
  • Dry mouth
  • Decreased blood pressure

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.


What drugs may interact with Novalgin® (metamizole, dipyrone)?

Novalgin® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

These following medicines should be alerted to your doctor:

  • Penicillin
  • Metformin
  • Glimepiride
  • Gliclazide
  • Glipizide
  • Warfarin (Farin)
  • Heparin
  • Nadroparin (Fraxiparin)
  • Prednisone
  • Methyl prednisolone
  • Dexamethasone
  • Methotrexate

Does food or alcohol interact with Novalgin® (metamizole, dipyrone)?

Do not apply tobacco and alcohol while you are on therapy with Novalgin®, because of the increased risk of side effects.

What health conditions may interact with Novalgin® (metamizole, dipyrone)?

Novalgin may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have, especially:

  • Trouble breathing (such as asthma)
  • Bone marrow damage
  • Genetic conditions, such as lack of certain enzymes (e.g., glucose 6 phosphate dehydrogenase)
  • Anemia
  • Liver or kidney damage
  • Ulcer in the stomach or duodenum
  • Cardiovascular disease (increased or decreased blood pressure, angina pectoris, heart failure, history of myocardial infarction or stroke)


The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using this medication.

What is the dose of Novalgin® (metamizole, dipyrone) for an adult?

For treating fever and/or severe pain


  • As metamizole Na: 1 g up to 4 times daily or 2.5 g twice a day given via IV injection over 5 minutes or via IM injection. Adjust dose based on severity and patient response. Max: 5 g daily.


  • As metamizole Na: 0.5-1 g up to 3-4 times daily. Max: 4 g daily. Max treatment duration: 3-5 days.

What is the dose of Novalgin® (metamizole, dipyrone) for a child?

For treating fever and/or severe pain


  • As methimazole Na: ≥3 months dosage varies based on body weight.
  • Refer to individual product literature for detailed guidelines.
  • As methimazole Na drops: ≥3 months dosage varies based on body weight.
  • Recommended dose: 8-16 mg/kg as a single dose, may repeat if necessary, up to 3 or 4 times daily.
  • Refer to individual product literature for detailed guidelines.

How is Novalgin® (metamizole, dipyrone) available?

Novalgin® is available in the following dosage forms and strengths: ampoules and tablets.

  • Tablet: 250 – 500 mg
  • Oral drop solution: 500 mg/ml

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services or go to your nearest emergency room.

Symptoms of overdose include nausea, vomiting, headache, dizziness, fainting, heart rate disturbance, kidney damage, and others.

What should I do if I miss a dose?

If you miss a dose of Novalgin®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.Novalgin. November 31, 2016

Hello Health Group does not provide medical advice, diagnosis or treatment.

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