Update Date 06/05/2020 . 4 mins read
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Know the basics

What is Combantrin® (Pyrantel) used for?

Combantrin® is an anthelmintics, commonly used for treat pinworms (enterobiasis; oxyuriasis) or  other worm infections. In some cases, Combantrin® can be prescribed to treat common roundworm infection; Hookworm infection and more than one worm infection at a time.

How should I take Combantrin® (Pyrantel)?

For orally taken form, you should:

  • Take Combantrin® by mouth as directed by your doctor concerning: dose, schedule.
  • Read the label carefully before using Combantrin®.
  • Consult your doctor for any information on the label that you do not clearly understand.

How do I store Combantrin® (Pyrantel)?

Combantrin® is best stored at room temperature away from direct light and moisture. To prevent drug damage, you should not store Combantrin® in the bathroom or the freezer. There may be different brands of Combantrin® that may have different storage needs. It is important to always check the product package for instructions on storage, or ask your pharmacist. For safety, you should keep all medicines away from children and pets.

You should not flush Combantrin® down the toilet or pour them into a drain unless instructed to do so. It is important to properly discard this product when it is expired or no longer needed. Consult your pharmacist for more details about how to safely discard your product.

Know the precautions & warnings

What should I know before using Combantrin® (Pyrantel)?

Before using Combantrin®, tell your doctor if you have:

  • Allergic reaction: to Combantrin®, excipients using for dosage form containing Combantrin®. The information is detailed in the leaflet.
  • Allergic reaction to any other medicines, foods, dyes, preservatives, or animals.
  • Pediatric.
  • Geriatric.
  • Used any other health conditions, drugs that have a risk of interaction with Combantrin®.

Is it safe during pregnancy or breastfeeding?

There are no adequate studies in women for determining risk when using Combantrin® during pregnancy or while breastfeeding. Please always consult with your doctor to weigh the potential benefits and risks before taking Combantrin®. Combantrin® (Pyrantel) is pregnancy risk category  C, according to the US Food and Drug Administration (FDA).

FDA pregnancy risk category reference below:

  • A=No risk;
  • B=No risk in some studies;
  • C=There may be some risk;
  • D=Positive evidence of risk;
  • X=Contraindicated;
  • N=Unknown.

Know the side effects

What side effects can occur from Combantrin® (Pyrantel)?

As taking others medicines, taking Combantrin® can cause some side effects. Most of them are rarely occurring and do not need any supplementary treatment. However, it is always important for you to consult your doctor if you have any problem after taking this medicine.

Some of the side effects are listed below:

  • Diarrhea; dizziness; a headache; nausea; stomach cramps; vomiting.
  • Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

Not everyone experiences these side effects. There may be some side effects not listed above. If you have any concerns about a side-effect, please consult your doctor or pharmacist.

Know the interactions

What drugs may interact with Combantrin® (Pyrantel)?

Combantrin® may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. To avoid any potential drug interactions, you should keep a list of all the drugs you are using (including prescription drugs, nonprescription drugs, and herbal products) and share it with your doctor and pharmacist. For your safety, do not start, stop, or change the dosage of any drugs without your doctor’s approval.

Does food or alcohol interact with Combantrin® (Pyrantel)?

Combantrin® may interact with food or alcohol by altering the way the drug works or increase the risk for serious side effects. Please discuss with your doctor or pharmacist any potential food or alcohol interactions before using this drug.

What health conditions may interact with Combantrin® (Pyrantel)?

Combantrin® may interact with your health condition. This interaction may worsen your health condition or alter the way the drug works. It is important to always let your doctor and pharmacist know all the health conditions you currently have.

Understand the dosage

The information provided is not a substitute for any medical advice. You should ALWAYS consult with your doctor or pharmacist before using Combantrin®.

What is the dose of Combantrin® (Pyrantel) for an adult?

Consult your doctor for information about the dose of Combantrin® hydrochloride.

Recommended doses in some cases are based on body weight and will be determined by your doctor. It is taken as a single dose and may need to be repeated in two to three weeks.

What is the dose of Combantrin® (Pyrantel) for a child?

Consult your doctor for information about the dose of Combantrin® hydrochloride.

Dosing instructions for 125 mg tablets and 125 mg/5mL syrup of Combantrin:

2 to less than 5 years: 1 tablet or 1 teaspoon (125 mg)

5-9 years: 2 tablets or 2 teaspoons (250 mg)

10-14 years: 3 tablets or 3 teaspoons (375 mg)

15 years or older: 4 tablets or 4 teaspoons (500 mg)

Not recommended for use in children less than 2 years.

How is Combantrin® (Pyrantel) available?

Combantrin® is available in the following dosage forms and strengths:

  • Suspension: 125 mg/5mL (10 mL)
  • Tablet: 125 mg

What should I do in case of an emergency or overdose?

In case of an emergency or an overdose, call your local emergency services (115) or go to your nearest emergency room.

What should I do if I miss a dose?

If you miss a dose of Combantrin®, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take your regular dose as scheduled. Do not take a double dose.

Hello Health Group does not provide medical advice, diagnosis or treatment.

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